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A New Triterpenoid from Teucrium viscidum

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收录情况： ◇ SCIE

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单位： [1]Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Pharm, Hubei Key Lab Nat Med Chem & Resource Evaluat, Wuhan 430030, Peoples R China [2]Huazhong Univ Sci & Technol, Tongji Med Coll, Tongji Hosp, Wuhan 430030, Peoples R China [3]Shanghai Pharmaceut Holding Co Ltd, Cent Res Inst, Shanghai 201203, Peoples R China

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关键词： Teucrium viscidum triterpenoids lignans 11 beta-HSD1

摘要：

A new ursane-type triterpenoid, 3 beta-hydroxy-urs-30-p-Z-hydroxycinnamoyloxy-12- en-28-oic-acid (1), together with three known triterpenoids, 3 beta-hydroxy-urs-30-p-E-hydroxycinnamoyloxy-12-en-28-oic-acid (2), 2 alpha, 3 beta, 19 alpha-trihydroxy-urs-12-en-28-oic-acid (3), and ursolic acid (4), four known lignans, pinoresinol (5), 9 alpha-hydroxypinoresinol (6), (+)-medioresinol (7), and (+)-kobusin (8), and two steroids, beta-sitosterol (9), and daucosterol (10), were isolated from the whole parts of Teucrium viscidum. Their structures were established by a combination of spectroscopic data analysis, besides comparison with literature data. Compounds 1-4 were evaluated for their inhibitory activities against 11 beta-hydroxysteroid dehydrogenase 1 (11 beta-HSD1).

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出版当年[2012]版：

大类 | 4 区化学

小类 | 4 区有机化学

最新[2025]版：

大类 | 3 区化学

小类 | 3 区生化与分子生物学 3 区化学：综合

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出版当年[2011]版：

Q2 CHEMISTRY, ORGANIC

最新[2023]版：

Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY Q2 CHEMISTRY, MULTIDISCIPLINARY

影响因子： 4.2 最新[2023版] 4.6 最新五年平均 2.386 出版当年[2011版] 2.411 出版当年五年平均 1.988 出版前一年[2010版] 2.428 出版后一年[2012版]

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第一作者单位： [1]Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Pharm, Hubei Key Lab Nat Med Chem & Resource Evaluat, Wuhan 430030, Peoples R China

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