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Expert consensus on the diagnosis and treatment of end-stage liver disease complicated by infections

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收录情况： ◇ SCIE

作者：
Chen Tao[1] * ; Chen Guang[1] ; Wang Guiqiang[2] ; Treeprasertsuk Sombat[3] ; Lesmana Cosmas Rinaldi Adithya[4] ; Lin Han-Chieh[5] ; Al-Mahtab Mamun[6] ; Chawla Yogesh K[7] ; Tan Soek-Siam[8] ; Kao Jia-Horng[9] ; Yuen Man-Fung[10] ; Lee Guan-Huei[11] ; Alcantara-Payawal Diana[12] ; Nakayama Nobuaki[13] ; Abbas Zaigham[14] ; Jafri Wasim[15] ; Kim Dong-Joon[16] ; Choudhury Ashok[17] ; Mahiwall Rakhi[17] ; Hou Jinlin[18] ; Hamid Saeed[15] ; Jia Jidong[19] ; Bajaj J S[20] ; Wang Fusheng[21] ; Sarin Shiv K[17] ; Ning Qin[1] ;
单位： [1]State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases,Department and Institute of Infectious Disease,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,1095,Jiefang Avenue,Wuhan 430030,P.R. China [2]Department of Infectious Disease, Center for Liver Disease, Peking University First Hospital, Beijing, China [3]Department of Medicine, Division of Gastroenterology, Faculty of Medicine, Chulalongkorn University, and Thai Red Cross, Bangkok, Thailand [4]Internal Medicine, Hepatobiliary Division, Dr. Captor Mangunkusumo National General Hospital, Universitas Indonesia, Jakarta, DKI, Indonesia [5]Faculty of Medicine, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan [6]Department of Hepatology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh [7]Department of Gastroenterology and Hepatology, Kalinga Institute of Medical Sciences, Bhubaneswar, India [8]Department of Hepatology, Hospital Selayang, Selangor Darul Ehsan, Malaysia [9]Graduate Institute of Clinical Medicine and Hepatitis Research Center, National Taiwan University College of Medicine and Hospital, Taipei, Taiwan [10]Department of Medicine, School of Clinical Medicine, The University of Hong Kong, Pokfulam, Hong Kong [11]Division of Gastroenterology and Hepatology, Department of Medicine, National University Hospital, Singapore, Singapore [12]Fatima University Medical Center Manila, Manila, Philippines [13]Department of Gastroenterology & Hepatology, Saitama Medical University, Saitama, Japan [14]Department of Medicine, Ziauddin University Hospital, Karachi, Pakistan [15]Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan [16]Department of Internal Medicine, Chuncheon Sacred Heart Hospital of Hallym University Medical Center, Chuncheon, Korea [17]Department of Hepatology, Institute of Liver and Biliary Sciences, New Delhi, India [18]Guangdong Provincial Key Laboratory of Viral Hepatitis Research, Guangdong Provincial Clinical Research Center for Viral Hepatitis, Key Laboratory of Infectious Diseases Research in South China, Ministry of Education, Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou, China [19]Liver Research Center, Beijing Friendship Hospital, Capital Medical University, Beijing, China [20]Department of Medicine, Virginia Commonwealth University and Central Virginia Veterans Healthcare System, Richmond, VA, USA [21]Senior Department of Infectious Diseases, The Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, China
出处：
DOI： 10.1007/s12072-023-10637-3
ISSN：

关键词： Cirrhosis Decompensation Infection Sepsis Antibiotics Acute decompensation ACLF Organ failure Septic shock Treatment Consensus

摘要：
End-stage liver disease (ESLD) is a life-threatening clinical syndrome and when complicated with infection the mortality is markedly increased. In patients with ESLD, bacterial or fungal infection can induce or aggravate the occurrence or progression of liver decompensation. Consequently, infections are among the most common complications of disease deterioration. There is an overwhelming need for standardized protocols for early diagnosis and appropriate management for patients with ESLD complicated by infections. Asia Pacific region has the largest number of ESLD patients, due to hepatitis B and the growing population of alcohol and NAFLD. Concomitant infections not only add to organ failure and high mortality but also to financial and healthcare burdens. This consensus document assembled up-to-date knowledge and experience from colleagues across the Asia-Pacific region, providing data on the principles as well as evidence-based current working protocols and practices for the diagnosis and treatment of patients with ESLD complicated by infections.© 2024. Asian Pacific Association for the Study of the Liver.

基金：
Supported by the National Key Research and Development Program of China (2021YFC2600200).
语种：
外文
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2023]版：
大类 | 2 区 医学
小类 | 3 区 胃肠肝病学
最新[2025]版：
大类 | 1 区 医学
小类 | 2 区 胃肠肝病学
JCR分区：
出版当年[2022]版：
Q1 GASTROENTEROLOGY & HEPATOLOGY
最新[2023]版：
Q1 GASTROENTEROLOGY & HEPATOLOGY

影响因子： 最新[2023版] 最新五年平均 出版当年[2022版] 出版当年五年平均 出版前一年[2021版] 出版后一年[2023版]

第一作者：
第一作者单位： [1]State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases,Department and Institute of Infectious Disease,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,1095,Jiefang Avenue,Wuhan 430030,P.R. China
通讯作者：
推荐引用方式(GB/T 7714)：
Chen Tao,Chen Guang,Wang Guiqiang,et al.Expert consensus on the diagnosis and treatment of end-stage liver disease complicated by infections[J].Hepatology International.2024,doi:10.1007/s12072-023-10637-3.
APA：
Chen Tao,Chen Guang,Wang Guiqiang,Treeprasertsuk Sombat,Lesmana Cosmas Rinaldi Adithya...&Ning Qin.(2024).Expert consensus on the diagnosis and treatment of end-stage liver disease complicated by infections.Hepatology International,,
MLA：
Chen Tao,et al."Expert consensus on the diagnosis and treatment of end-stage liver disease complicated by infections".Hepatology International .(2024)

相关文献

[1]Definition of ACLF and inclusion criteria for extra-hepatic organ failure [2]Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific association for the study of the liver (APASL): an update [3]Liver failure determines the outcome in patients of acute-on-chronic liver failure (ACLF): comparison of APASL ACLF research consortium (AARC) and CLIF-SOFA models [4]Individualized resuscitation strategy for septic shock formalized by finite mixture modeling and dynamic treatment regimen [5]Early immune system alterations in patients with septic shock [6]Anisodamine hydrobromide in the treatment of critically ill patients with septic shock: a multicenter randomized controlled trial [7]Epidemiology and Outcome of Severe Sepsis and Septic Shock in Intensive Care Units in Mainland China [8]Targeted Inhibition of FTO Demethylase Protects Mice Against LPS-Induced Septic Shock by Suppressing NLRP3 Inflammasome [9]Intrinsic/extrinsic apoptosis and pyroptosis contribute to the selective depletion of B cell subsets in septic shock patients [10]Anisodamine Critically Ill SeptIc Shock

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