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Current Progress in Breast Implant-Associated Anaplastic Large Cell Lymphoma

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单位: [1]Huazhong Univ Sci & Technol, Tongji Hosp, Dept Plast & Cosmet Surg, Tongji Med Coll, Wuhan, Peoples R China
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关键词: BIA-ALCL epidemiology genetic predisposition bacterial contamination implant modification

摘要:
Breast implant-associated anaplastic large-cell lymphoma (BIA-ALCL) is an uncommon type of T-cell lymphoma. Although with a low incidence, the epidemiological data raised the biosafety and health concerns of breast reconstruction and breast augmentation for BIA-ALCL. Emerging evidence confirms that genetic features, bacterial contamination, chronic inflammation, and textured breast implant are the relevant factors leading to the development of BIA-ALCL. Almost all reported cases with a medical history involve breast implants with a textured surface, which reflects the role of implant surface characteristics in BIA-ALCL. With this review, we expect to highlight the most significant features on etiology, pathogenesis, diagnosis, and therapy of BIA-ALCL, as well as we review the physical characteristics of breast implants and their potential pathogenic effect and hopefully provide a foundation for optimal choice of type of implant with minimal morbidity.

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出版当年[2021]版:
大类 | 3 区 医学
小类 | 3 区 肿瘤学
最新[2025]版:
大类 | 3 区 医学
小类 | 4 区 肿瘤学
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出版当年[2020]版:
Q2 ONCOLOGY
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Q2 ONCOLOGY

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第一作者单位: [1]Huazhong Univ Sci & Technol, Tongji Hosp, Dept Plast & Cosmet Surg, Tongji Med Coll, Wuhan, Peoples R China
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