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AI detection of mild COVID-19 pneumonia from chest CT scans

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单位: [1]Univ Chinese Acad Sci, Canc Hosp, Zhejiang Canc Hosp, 1 East Banshan Rd, Hangzhou, Zhejiang, Peoples R China [2]Chinese Acad Sci, Inst Basic Med & Canc IBMC, Hangzhou, Peoples R China [3]Huazhong Univ Sci & Technol, Tongji Hosp, Dept Resp & Crit Care Med, Tongji Med Coll, Wuhan, Peoples R China [4]Jianghan Univ, Huangpi Peoples Hosp, Dept Infect Med, Wuhan, Peoples R China [5]Vanderbilt Univ, Med Ctr, Dept Biostat, Nashville, TN USA [6]Zhejiang Prov Peoples Hosp, Dept Resp Med, Hangzhou, Peoples R China
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关键词: Computer-assisted diagnosis Volume CT COVID-19 Artificial intelligence Deep learning

摘要:
Objectives An artificial intelligence model was adopted to identify mild COVID-19 pneumonia from computed tomography (CT) volumes, and its diagnostic performance was then evaluated. Methods In this retrospective multicenter study, an atrous convolution-based deep learning model was established for the computer-assisted diagnosis of mild COVID-19 pneumonia. The dataset included 2087 chest CT exams collected from four hospitals between 1 January 2019 and 31 May 2020. The true positive rate, true negative rate, receiver operating characteristic curve, area under the curve (AUC) and convolutional feature map were used to evaluate the model. Results The proposed deep learning model was trained on 1538 patients and tested on an independent testing cohort of 549 patients. The overall sensitivity was 91.5% (195/213; p < 0.001, 95% CI: 89.2-93.9%), the overall specificity was 90.5% (304/336; p < 0.001, 95% CI: 88.0-92.9%) and the general AUC value was 0.955 (p < 0.001). Conclusions A deep learning model can accurately detect COVID-19 and serve as an important supplement to the COVID-19 reverse transcription-polymerase chain reaction (RT-PCR) test.

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出版当年[2020]版:
大类 | 2 区 医学
小类 | 2 区 核医学
最新[2025]版:
大类 | 2 区 医学
小类 | 2 区 核医学
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出版当年[2019]版:
Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
最新[2023]版:
Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

影响因子: 最新[2023版] 最新五年平均 出版当年[2019版] 出版当年五年平均 出版前一年[2018版] 出版后一年[2020版]

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第一作者单位: [1]Univ Chinese Acad Sci, Canc Hosp, Zhejiang Canc Hosp, 1 East Banshan Rd, Hangzhou, Zhejiang, Peoples R China [2]Chinese Acad Sci, Inst Basic Med & Canc IBMC, Hangzhou, Peoples R China
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通讯机构: [1]Univ Chinese Acad Sci, Canc Hosp, Zhejiang Canc Hosp, 1 East Banshan Rd, Hangzhou, Zhejiang, Peoples R China [2]Chinese Acad Sci, Inst Basic Med & Canc IBMC, Hangzhou, Peoples R China [6]Zhejiang Prov Peoples Hosp, Dept Resp Med, Hangzhou, Peoples R China
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