Objectives An artificial intelligence model was adopted to identify mild COVID-19 pneumonia from computed tomography (CT) volumes, and its diagnostic performance was then evaluated. Methods In this retrospective multicenter study, an atrous convolution-based deep learning model was established for the computer-assisted diagnosis of mild COVID-19 pneumonia. The dataset included 2087 chest CT exams collected from four hospitals between 1 January 2019 and 31 May 2020. The true positive rate, true negative rate, receiver operating characteristic curve, area under the curve (AUC) and convolutional feature map were used to evaluate the model. Results The proposed deep learning model was trained on 1538 patients and tested on an independent testing cohort of 549 patients. The overall sensitivity was 91.5% (195/213; p < 0.001, 95% CI: 89.2-93.9%), the overall specificity was 90.5% (304/336; p < 0.001, 95% CI: 88.0-92.9%) and the general AUC value was 0.955 (p < 0.001). Conclusions A deep learning model can accurately detect COVID-19 and serve as an important supplement to the COVID-19 reverse transcription-polymerase chain reaction (RT-PCR) test.
基金:
Zhejiang Provincial Natural Science Foundation of China [LZY21F030001]; National Natural Science Foundation of China [81870028, 81871370]; Zhejiang provincial program for the Cultivation of High-level Innovative Health Talents [A-2017-CXCR02]
第一作者单位:[1]Univ Chinese Acad Sci, Canc Hosp, Zhejiang Canc Hosp, 1 East Banshan Rd, Hangzhou, Zhejiang, Peoples R China[2]Chinese Acad Sci, Inst Basic Med & Canc IBMC, Hangzhou, Peoples R China
通讯作者:
通讯机构:[1]Univ Chinese Acad Sci, Canc Hosp, Zhejiang Canc Hosp, 1 East Banshan Rd, Hangzhou, Zhejiang, Peoples R China[2]Chinese Acad Sci, Inst Basic Med & Canc IBMC, Hangzhou, Peoples R China[6]Zhejiang Prov Peoples Hosp, Dept Resp Med, Hangzhou, Peoples R China
推荐引用方式(GB/T 7714):
Yao Jin-Cao,Wang Tao,Hou Guang-Hua,et al.AI detection of mild COVID-19 pneumonia from chest CT scans[J].EUROPEAN RADIOLOGY.2021,31(9):7192-7201.doi:10.1007/s00330-021-07797-x.
APA:
Yao, Jin-Cao,Wang, Tao,Hou, Guang-Hua,Ou, Di,Li, Wei...&Li, Ya-Qing.(2021).AI detection of mild COVID-19 pneumonia from chest CT scans.EUROPEAN RADIOLOGY,31,(9)
MLA:
Yao, Jin-Cao,et al."AI detection of mild COVID-19 pneumonia from chest CT scans".EUROPEAN RADIOLOGY 31..9(2021):7192-7201