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The role of microglia in chronic pain and depression: innocent bystander or culprit?

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单位: [1]Nanjing Med Univ, Affiliated Stomatol Hosp, Dept Anesthesiol, Nanjing 210029, Peoples R China [2]Nanjing Med Univ, Dept Anesthesiol, Affiliated Changzhou Peoples Hosp 2, Changzhou 213000, Peoples R China [3]Nanjing Med Univ, Dept Anesthesiol & Perioperat Med, Affiliated Hosp 1, Nanjing 210029, Peoples R China [4]Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Dept Anesthesiol, Wuhan 430030, Peoples R China
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关键词: Microglia Chronic pain Depression

摘要:
Clinical evidence shows that chronic pain and depression often accompany each other, but the underlying pathogenesis of comorbid chronic pain and depression remains mostly undetermined. Biotechnology is gradually revealing the phenotype and function of microglia, with great progress regarding microglia's role in neurodegeneration, depression, chronic pain, and other conditions. This article summarizes the role of microglia in chronic pain, depression, and comorbidities, which is conducive to finding new targets to treat chronic pain and depression.

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出版当年[2020]版:
大类 | 3 区 医学
小类 | 3 区 神经科学 3 区 药学 3 区 精神病学
最新[2025]版:
大类 | 3 区 医学
小类 | 3 区 神经科学 3 区 药学 3 区 精神病学
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出版当年[2019]版:
Q2 PSYCHIATRY Q2 PHARMACOLOGY & PHARMACY Q2 NEUROSCIENCES
最新[2023]版:
Q2 NEUROSCIENCES Q2 PHARMACOLOGY & PHARMACY Q2 PSYCHIATRY

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第一作者单位: [1]Nanjing Med Univ, Affiliated Stomatol Hosp, Dept Anesthesiol, Nanjing 210029, Peoples R China
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