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A comparison of the clinical characteristics of women with recurrent major depression with and without suicidal symptomatology

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单位: [1]China Med Univ, Dept Psychiat, Hosp 1, Shenyang 110001, Peoples R China; [2]ZheJiang Tradit Chinese Med Hosp, Hangzhou, Zhejiang, Peoples R China; [3]Zhejiang Chinese Med Univ, Affiliated Hosp 2, Hangzhou, Zhejiang, Peoples R China; [4]Zhengzhou Univ, Hosp 1, Zhengzhou, Peoples R China; [5]Shandong Mental Hlth Ctr, Jinan, Shan Dong, Peoples R China; [6]Capital Med Univ, Beijing Anding Hosp, Beijing, Peoples R China; [7]Xi An Jiao Tong Univ, Coll Med, Hosp 1, Xian 710049, Shaan Xi, Peoples R China; [8]Shanxi Med Univ, Hosp 1, Xian, Shanxi, Peoples R China; [9]China Med Univ, ShengJing Hosp, Liaoning, Peoples R China; [10]Zhongshan Univ, Affiliated Hosp 3, Guangzhou, Guangdong, Peoples R China; [11]Jiangsu Univ, Affiliated Hosp 4, Zhenjiang, Jiangsu, Peoples R China; [12]Jilin Brain Hosp, Jilin, Peoples R China; [13]Tianjin Anding Hosp, Tianjin, Peoples R China; [14]Affiliated Harbin Med Univ, Mental Hlth Ctr 1, Heilongjiang, Peoples R China; [15]Chongqing Mental Hlth Ctr, Chongqing, Peoples R China; [16]Dalian 7 Peoples Hosp, Dalian, Peoples R China; [17]Dalian Mental Hlth Ctr, Dalian, Peoples R China; [18]Shenzhen Kangning Hosp, Shenzhen, Peoples R China; [19]Nanjing Brain Hosp, Nanjing, Jiangsu, Peoples R China; [20]Hebei Med Univ, Hosp 1, Shijiazhuang, Peoples R China; [21]Sichuan Mental Hlth Ctr, Chengdu, Sichuan, Peoples R China; [22]Lanzhou Univ, Clin Med Coll 2, Hosp 2, Lanzhou, Gansu Province, Peoples R China; [23]Chongqing Med Univ, Hosp 1, Chongqing, Peoples R China; [24]Sichuan Univ, W China Hosp, Mental Hlth Ctr, Chengdu, Si Chuan, Peoples R China; [25]Shanghai Tongji Univ, Affiliated Tongji Hosp, Shanghai, Peoples R China; [26]Shanghai Jiao Tong Univ, Sch Med, Affiliated Shanghai Mental Hlth Ctr, Shanghai 200030, Peoples R China; [27]Fudan Univ, Affiliated Huashan Hosp, Shanghai 200433, Peoples R China; [28]Wuhan Mental Hlth Ctr, Wuhan, Hubei, Peoples R China; [29]3 Hosp Heilongjiang Prov, Heilongjiang, Peoples R China; [30]Jinan Univ, Affiliated Hosp 1, Guangzhou, Guangdong, Peoples R China; [31]Ningbo Kangning Hosp, Ningbo, Zhejiang, Peoples R China; [32]Suzhou Guangji Hosp, Suzhou, Jiangsu, Peoples R China; [33]Fourth Mil Med Univ, Affiliated Xijing Hosp, Xian, Shaanxi, Peoples R China; [34]Guangzhou Psychiat Hosp, Guangzhou Brain Hosp, Guangzhou, Guangdong, Peoples R China; [35]4 Peoples Hosp Liaocheng, Liaocheng, Shandong, Peoples R China; [36]Xian Mental Hlth Ctr, Xian, Shanxi, Peoples R China; [37]Wellcome Trust Ctr Human Genet, Oxford, England; [38]Radcliffe Infirm, Clin Trial Serv Unit, Oxford OX2 6HE, England; [39]Virginia Commonwealth Univ, Dept Psychiat, Virginia Inst Psychiat & Behav Genet, Richmond, VA USA; [40]China Med Univ, Dept Psychiat, Hosp 1, 155 Nanjing N St, Shenyang 110001, Peoples R China
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关键词: Co-morbidity major depression suicidal ideation suicide women

摘要:
Background. The relationship between recurrent major depression (MD) in women and suicidality is complex. We investigated the extent to which patients who suffered with various forms of suicidal symptomatology can be distinguished from those subjects without such symptoms. Method. We examined the clinical features of the worst episode in 1970 Han Chinese women with recurrent DSM-IV MD between the ages of 30 and 60 years from across China. Student's t tests, and logistic and multiple logistic regression models were used to determine the association between suicidality and other clinical features of MD. Results. Suicidal symptomatology is significantly associated with a more severe form of MD, as indexed by both the number of episodes and number of MD symptoms. Patients reporting suicidal thoughts, plans or attempts experienced a significantly greater number of stressful life events. The depressive symptom most strongly associated with lifetime suicide attempt was feelings of worthlessness (odds ratio 4.25, 95% confidence interval 2.9-6.3). Excessive guilt, diminished concentration and impaired decision-making were also significantly associated with a suicide attempt. Conclusions. This study contributes to the existing literature on risk factors for suicidal symptomatology in depressed women. Identifying specific depressive symptoms and co-morbid psychiatric disorders may help improve the clinical assessment of suicide risk in depressed patients. These findings could be helpful in identifying those who need more intense treatment strategies in order to prevent suicide.

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出版当年[2011]版:
大类 | 2 区 医学
小类 | 2 区 精神病学 2 区 心理学
最新[2025]版:
大类 | 2 区 医学
小类 | 1 区 心理学 1 区 心理学:临床 2 区 精神病学
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出版当年[2010]版:
Q1 PSYCHIATRY Q1 PSYCHOLOGY Q1 PSYCHOLOGY, CLINICAL
最新[2023]版:
Q1 PSYCHIATRY Q1 PSYCHOLOGY Q1 PSYCHOLOGY, CLINICAL

影响因子: 最新[2023版] 最新五年平均 出版当年[2010版] 出版当年五年平均 出版前一年[2009版] 出版后一年[2011版]

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