In the current paper, through utilizing two symmetrical pentacarboxylate ligands, namely, 3,5-di(2 ' ,5 ' -dicar- boxylphenyl)benzoic (H 5 L 1 ) and 3,5-di(2 ' ,4 ' dicarboxylphenyl)benzoic acid (H 5 L 2 ), two fresh Co(II)-basd coordination polymers (CPs), [Co 5 (mu 3 -H 2 O) 2 (L1) 2 ]& sdot;3DMA & sdot;4H 2 O ( 1 , DMA is N, N -dimethylacetamide) along with [Co 3 (mu 3 -OH)L2(H 2 O) 3 ]& sdot;H 2 O ( 2 ) have been synthesized under the conditions of solvothermal. With hyaluronic acid (HA) and carboxymethyl chitosan (CMCS) as raw materials, HA/CMCS hydrogel was prepared by chemical synthesis and its internal microstructure was observed by scanning electron microscope. Using bleomycin as a drug model, we designed and synthesized two metallogel particle frameworks encapsulating bleomycin drugs and compared the effects of the two metallogel particle frameworks as drug carriers for delivering bleomycin drugs for the treatment of hemangiomas.
第一作者单位：[1]Shanxi Med Univ, Hosp 3, Shanxi Bethune Hosp, Tongji Shanxi Hosp,Shanxi Acad Med Sci,Dept Vasc S, Taiyuan, Shanxi, Peoples R China[2]Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Wuhan, Hubei, Peoples R China
通讯作者：
通讯机构：[1]Shanxi Med Univ, Hosp 3, Shanxi Bethune Hosp, Tongji Shanxi Hosp,Shanxi Acad Med Sci,Dept Vasc S, Taiyuan, Shanxi, Peoples R China[2]Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Wuhan, Hubei, Peoples R China
推荐引用方式(GB/T 7714)：
Wang Shengquan,Sun Lei,Gao Hongxia,et al.Treatment activity of hydrogels loaded with metal-organic frameworks of bleomycin on hemangioma[J].INORGANICA CHIMICA ACTA.2024,566:doi:10.1016/j.ica.2024.122009.
APA：
Wang, Shengquan,Sun, Lei,Gao, Hongxia&Zhang, Wenpei.(2024).Treatment activity of hydrogels loaded with metal-organic frameworks of bleomycin on hemangioma.INORGANICA CHIMICA ACTA,566,
MLA：
Wang, Shengquan,et al."Treatment activity of hydrogels loaded with metal-organic frameworks of bleomycin on hemangioma".INORGANICA CHIMICA ACTA 566.(2024)
