个人科研网厅 | | 帮助
高级检索
当前位置： 首页 > 详情页

Prognostic significance of positive peritoneal cytology in endometrial carcinoma based on ESGO/ESTRO/ESP risk classification: A multicenter retrospective study

| 导出 | |

文献详情

资源类型：
WOS体系：
Pubmed体系：

收录情况： ◇ SCIE

作者：
Zhang Yue[1,2] * ; Chu Ran[1,2] * ; Zhang Zhaoyang[1,2] * ; Xu Congjian[6] * ; Liu Jihong[7] * ; Zhang Jieqing[8] * ; Wang Jianliu[9] * ; Wang Qiannan[1,2] ; Liu Chang[1,2] ; Feng Jie[1,2] ; Yao Qin[10] ; Yao Shuzhong[11] ; Xue Fengxia[12] ; Guo Hongyan[13] ; Xia Min[14] ; Wang Xipeng[15] ; Zhao Weidong[16] ; Li Xiaomao[17] ; Lin Bei[18] ; Zhao Xia[19] ; Ma Jiezhi[20] ; Zhang Ping[21] ; Guo Ruixia[22] ; Gao Qinglei[3,4] ; Sun Chaoyang[3,4] ; Ma Ding[3,4] ; Kong Beihua[1,2] ; Li Yang[5,*3] ; Chen Gang[3,4,*2] ; Song Kun[1,2,*1] ;
单位： [1]Department of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan 250012, China [2]Division of Gynecology oncology, Qilu Hospital of Shandong University, Jinan 250012, China [3]Cancer Biology Research Center (Key Laboratory of the Ministry of Education),Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,Hubei 430030,China [4]Department of Gynecology and Obstetrics,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,Hubei 430030,China [5]Department of Gynecologic Oncology, Women’s Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310006, China [6]Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai 250023, China [7]Department of Gynecologic Oncology, Sun Yat-sen University Cancer Center, Guangzhou 510060, China [8]Department of Gynecologic Oncology, Guangxi Medical University Cancer Hospital, Nanning 530021, China [9]Peking University People's Hospital, Beijing 100044, China [10]Department of Obstetrics and Gynecology, The Affiliated Hospital of Qingdao University, Qingdao 266003, China [11]Department of Obstetrics and Gynecology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China [12]Department of Gynecology and Obstetrics, Tianjin Medical University General Hospital, Tianjin 300052, China [13]The Third Hospital of Peking University, Beijing 100191, China [14]Department 0f Gynecology and Obstetrics, The Affiliated Yantai Yuhuangding Hospital of Qindao University, Yantai 264000, China [15]Department of Gynecology and Obstetrics, XinHua Hospital, Shanghai JiaoTong University School of Medicine, Shanghai 200092, China [16]The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, China [17]Department of Gynecology and Obstetrics, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 510630, China [18]Department of Obstetrics and Gynecology, Shengjing Hospital Affiliated to China Medical University, Shenyang 110004, China [19]Department of Gynecology and Obstetrics, Development and Related Disease of Women and Children Key Laboratory of Sichuan Province, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second Hospital, Sichuan University, Chengdu 610041, China [20]Department of Obstetrics and Gynecology, Xiangya Third Hospital, Central South University, Changsha, Hunan 410013, China [21]Department of Gynecology, The Second Hospital of Shandong University, Jinan 250033, China [22]Department of Gynecology and Obstetrics, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China
出处：
DOI： 10.1016/j.ygyno.2023.06.578
ISSN：

关键词： Endometrial carcinoma Positive peritoneal cytology ESGO/ESTRO/ESP risk classification Prognosis

摘要：
This study aimed to determine the prognostic significance of positive peritoneal cytology (PC) on endometrial carcinoma (EC) patients under the ESGO/ESTRO/ESP risk classification.This study retrospectively analyzed EC patients from 27 medical centers in China from 2000 to 2019. Patients were divided into three ESGO risk groups: low-risk, intermediate-risk and high-intermediate risk, and high-risk groups. The covariates were balanced by using the propensity score-based inverse probability of treatment weighting (PS-IPTW). The prognostic significance of PC was assessed by Kaplan-Meier curves and multivariate Cox regression analysis.A total of 6313 EC patients with PC results were included and positive PC was reported in 384 women (6.1%). The multivariate Cox analysis in all patients showed the positive PC was significantly associated with decreased PFS (hazard ratio [HR] 2.20, 95% confidence interval [CI] 1.55-3.13, P < 0.001) and OS (HR 2.25, 95% CI 1.49-3.40, P < 0.001),and the Kaplan-Meier curves also showed a poor survival in the intermediate and high-intermediate risk group (5-year PFS: 75.5% vs. 93.0%, P < 0.001; 5-year OS: 78.3% vs. 96.4%, P < 0.001); While in the low-risk group, there were no significant differences in PFS and OS between different PC status (5-year PFS: 93.1% vs. 97.3%, P = 0.124; 5-year OS: 98.6% vs. 98.2%, P = 0.823); in the high-risk group, significant difference was only found in PFS (5-year PFS: 62.5% vs. 77.9%, P = 0.033).Positive PC was an adverse prognostic factor for EC, especially in the intermediate and high-intermediate risk patients. Gynecologic oncologists should reconsider the effect of positive PC on different ESGO risk groups.Copyright © 2023 Elsevier Inc. All rights reserved.

基金：
This work was supported by the National Key Technology R&D Program of China (grant numbers (grant numbers 2022YFC2704200 and 2022YFC2704202); ECCM Program of Clinical Research Center of Shandong University (grant numbers 2021SDUCRCB012).
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2022]版：
大类 | 2 区 医学
小类 | 1 区 妇产科学 2 区 肿瘤学
最新[2025]版：
大类 | 2 区 医学
小类 | 1 区 妇产科学 2 区 肿瘤学
JCR分区：
出版当年[2021]版：
Q1 OBSTETRICS & GYNECOLOGY Q2 ONCOLOGY
最新[2023]版：
Q1 OBSTETRICS & GYNECOLOGY Q1 ONCOLOGY

影响因子： 最新[2023版] 最新五年平均 出版当年[2021版] 出版当年五年平均 出版前一年[2020版] 出版后一年[2022版]

第一作者：
第一作者单位： [1]Department of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan 250012, China [2]Division of Gynecology oncology, Qilu Hospital of Shandong University, Jinan 250012, China
共同第一作者：
通讯作者：
通讯机构： [1]Department of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan 250012, China [2]Division of Gynecology oncology, Qilu Hospital of Shandong University, Jinan 250012, China [3]Cancer Biology Research Center (Key Laboratory of the Ministry of Education),Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,Hubei 430030,China [4]Department of Gynecology and Obstetrics,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,Hubei 430030,China [5]Department of Gynecologic Oncology, Women’s Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310006, China [*1]Department of Obstetrics and Gynecology, Qilu Hospital of Shandong University, 107Wenhua Xi Road, Ji'nan 250012, Shandong Province, China. [*2]Department of Gynecology and Obstetrics,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,Hubei 430030,China [*3]Department of Gynecologic Oncology,Women's Hospital, Zhejiang University, School of Medicine, Xueshi Road 1, Hangzhou, Zhejiang 310006, China.
推荐引用方式(GB/T 7714)：
Zhang Yue,Chu Ran,Zhang Zhaoyang,et al.Prognostic significance of positive peritoneal cytology in endometrial carcinoma based on ESGO/ESTRO/ESP risk classification: A multicenter retrospective study[J].GYNECOLOGIC ONCOLOGY.2023,176:43-52.doi:10.1016/j.ygyno.2023.06.578.
APA：
Zhang Yue,Chu Ran,Zhang Zhaoyang,Xu Congjian,Liu Jihong...&Song Kun.(2023).Prognostic significance of positive peritoneal cytology in endometrial carcinoma based on ESGO/ESTRO/ESP risk classification: A multicenter retrospective study.GYNECOLOGIC ONCOLOGY,176,
MLA：
Zhang Yue,et al."Prognostic significance of positive peritoneal cytology in endometrial carcinoma based on ESGO/ESTRO/ESP risk classification: A multicenter retrospective study".GYNECOLOGIC ONCOLOGY 176.(2023):43-52

相关文献

[1]The effects of uterine manipulators in minimally invasive hysterectomy for endometrial cancer: A systematic review and meta-analysis [2]雌激素受体α异构体在子宫内膜癌组织中表达及与肿瘤预后的相关性分析 [3]Identification of Risk Factors of Multidrug-Resistant Tuberculosis by using Classification Tree Method [4]Development and validation of prediction model for early warning of ovarian metastasis risk of endometrial carcinoma [5]Proteogenomic insights into early-onset endometrioid endometrial carcinoma: predictors for fertility-sparing therapy response [6]Clinical Application of a New Cesarean Scar Pregnancy Classification and Evaluation System and a Risk Scoring System [7]Integrating pathology, chromosomal instability and mutations for risk stratification in early-stage endometrioid endometrial carcinoma [8]A novel cuproptosis-related gene signature for overall survival prediction in uterine corpus endometrial carcinoma (UCEC) [9]The Safety of Ovarian Preservation in Stage IA Endometrial Carcinoma (EC-02) [10]MiR-223 suppresses endometrial carcinoma cells proliferation by targeting IGF-1R

资源点击量：432 今日访问量：0 总访问量：412 更新日期：2025-04-01 建议使用谷歌、火狐浏览器 常见问题

版权所有：重庆聚合科技有限公司 渝ICP备12007440号-3 地址：重庆市两江新区泰山大道西段8号坤恩国际商务中心16层（401121）