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Type 2 Diabetes Mellitus Easily Develops into Alzheimer's Disease via Hyperglycemia and Insulin Resistance

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收录情况: ◇ SCIE ◇ 卓越:梯队期刊

单位: [1]Huazhong Univ Sci & Technol, Sch Basic Med, Dept Pathophysiol, Wuhan 430030, Peoples R China [2]Huazhong Univ Sci & Technol, Collaborat Innovat Ctr Brain Sci, Minist Educ China & Hubei Prov Neurol Disorders, Key Lab,Tongji Med Coll, Wuhan 430030, Peoples R China [3]Huazhong Univ Sci & Technol,Tongji Med Coll,Tongji Hosp,Inst Pathol,Wuhan 430030,Peoples R China
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关键词: type 2 diabetes mellitus Alzheimer's disease hyperglycemia insulin resistance cognition

摘要:
With the acceleration of population aging, the incidence of type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD) is progressively increasing due to the age-relatedness of these two diseases. The association between T2DM and AD-like dementia is receiving much attention, and T2DM is reported to be a significant risk factor for AD. The aims of this review were to reveal the brain changes caused by T2DM as well as to explore the roles of hyperglycemia and insulin resistance in the development of AD.

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出版当年[2020]版:
大类 | 4 区 医学
小类 | 4 区 医学:研究与实验
最新[2025]版:
大类 | 4 区 医学
小类 | 4 区 医学:研究与实验
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出版当年[2019]版:
Q4 MEDICINE, RESEARCH & EXPERIMENTAL
最新[2023]版:
Q3 MEDICINE, RESEARCH & EXPERIMENTAL

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第一作者单位: [1]Huazhong Univ Sci & Technol, Sch Basic Med, Dept Pathophysiol, Wuhan 430030, Peoples R China [2]Huazhong Univ Sci & Technol, Collaborat Innovat Ctr Brain Sci, Minist Educ China & Hubei Prov Neurol Disorders, Key Lab,Tongji Med Coll, Wuhan 430030, Peoples R China
通讯作者:
通讯机构: [1]Huazhong Univ Sci & Technol, Sch Basic Med, Dept Pathophysiol, Wuhan 430030, Peoples R China [2]Huazhong Univ Sci & Technol, Collaborat Innovat Ctr Brain Sci, Minist Educ China & Hubei Prov Neurol Disorders, Key Lab,Tongji Med Coll, Wuhan 430030, Peoples R China
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