BackgroundThis study aimed to establish nomogram models of overall survival (OS) and cancer-specific survival (CSS) in elderly colorectal cancer (ECRC) patients (Age >= 70).MethodsThe clinical variables of patients confirmed as ECRC between 2004 and 2016 were retrieved from the Surveillance, Epidemiology, and End Results (SEER) database. Univariate and multivariate analysis were performed, followed by the construction of nomograms in OS and CSS.ResultsA total of 44,761 cases were finally included in this study. Both C-index and calibration plots indicated noticeable performance of newly established nomograms. Moreover, nomograms also showed higher outcomes of decision curve analysis (DCA) and the area under the curve (AUC) compared to American Joint Committee on Cancer (AJCC) tumor-node-metastasis (TNM) stage and SEER stage.ConclusionsThis study established nomograms of elderly colorectal cancer patients with distinct clinical values compared to AJCC TNM and SEER stages regarding both OS and CSS.
第一作者单位：[1]Fudan Univ, Shanghai Canc Ctr, Dongan Rd 270, Shanghai 200025, Peoples R China[2]Fudan Univ, Dept Oncol, Shanghai Med Coll, Dongan Rd 270, Shanghai 200025, Peoples R China
通讯作者：
通讯机构：[1]Fudan Univ, Shanghai Canc Ctr, Dongan Rd 270, Shanghai 200025, Peoples R China[2]Fudan Univ, Dept Oncol, Shanghai Med Coll, Dongan Rd 270, Shanghai 200025, Peoples R China
推荐引用方式(GB/T 7714)：
Yu Chaoran,Zhang Yujie.Establishment of prognostic nomogram for elderly colorectal cancer patients: a SEER database analysis[J].BMC GASTROENTEROLOGY.2020,20(1):doi:10.1186/s12876-020-01464-z.
APA：
Yu, Chaoran&Zhang, Yujie.(2020).Establishment of prognostic nomogram for elderly colorectal cancer patients: a SEER database analysis.BMC GASTROENTEROLOGY,20,(1)
MLA：
Yu, Chaoran,et al."Establishment of prognostic nomogram for elderly colorectal cancer patients: a SEER database analysis".BMC GASTROENTEROLOGY 20..1(2020)
