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Ablation as First-Line Therapy for Atrial Fibrillation: Yes

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单位： [a]Texas Cardiac Arrhythmia Institute, St David's Medical Center, 3000 North I-35, Suite 720, Austin, TX 78705, United States [b]University of Foggia, Foggia, Italy [c]Division of Cardiology, Stanford University, 300 Pasteur Drive, MC 5319 A260, Stanford, CA, United States [d]Department of Internal Medicine, Tong-Ji Hospital, Tong-Ji Medical College, Huazhong University of Science and Technology, Wuhan, China [e]Heart Institute, Faculty of Medicine, University of Pecs, Pecs, Hungary [f]Heart and Vascular Center, Case Western Reserve University School of Medicine, 2500 MetroHealth Drive, Cleveland, OH 44109, United States [g]Interventional Electrophysiology, Scripps Clinic, San Diego, CA, United States [h]EP Services, California Pacific Medical Center, San Francisco, CA, United States

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关键词： Atrial fibrillation Catheter ablation First-line therapy

摘要：

This article addresses the use of catheter ablation (CA) as first-line therapy for atrial fibrillation (AF). CA increases long-term freedom from AF, reduces hospitalizations, and improves quality of life compared with antiarrhythmic drug (AAD) therapy in patients with symptomatic AF who have already failed one AAD. The role of CA as first-line therapy for AF, however, is still controversial. Evidence from randomized controlled trials shows that CA is definitely superior to AADs as first-line therapy for relatively young patients with paroxysmal AF, with comparable complication rates and results consistently reproducible across different institutions, operators, and types of ablation approaches. © 2012 Elsevier Inc.

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第一作者单位： [a]Texas Cardiac Arrhythmia Institute, St David's Medical Center, 3000 North I-35, Suite 720, Austin, TX 78705, United States [b]University of Foggia, Foggia, Italy

通讯作者：

通讯机构： [a]Texas Cardiac Arrhythmia Institute, St David's Medical Center, 3000 North I-35, Suite 720, Austin, TX 78705, United States [c]Division of Cardiology, Stanford University, 300 Pasteur Drive, MC 5319 A260, Stanford, CA, United States [f]Heart and Vascular Center, Case Western Reserve University School of Medicine, 2500 MetroHealth Drive, Cleveland, OH 44109, United States [g]Interventional Electrophysiology, Scripps Clinic, San Diego, CA, United States [h]EP Services, California Pacific Medical Center, San Francisco, CA, United States

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Ablation as First-Line Therapy for Atrial Fibrillation: Yes

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