单位：[a]Department of Neurosurgery, Second Affiliated Hospital of Nanchang University, Nanchang, 330006, China[b]Department of Neurosurgery, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, 430030, China华中科技大学同济医学院附属同济医院外科学系神经外科
Ethnopharmacological relevance Hedyotis diffusa Willd (Rubiaceae) (HDW) has been widely applied for the treatment of tumors, inflammation and toxication in traditional Chinese medicine. The antitumor effect of HDW on glioblastoma has been rarely reported. We aim to evaluate the activity of this extract and explore the underlying mechanism in U87 human glioblastoma cell line.
基金：
The research was supported in part by National Natural Science Foundation of China (No. 81372711 ) and the National Clinical Key Specialty Construction Project . We thank Huifang Liang for kindly providing experimental materials.
语种：
外文
PubmedID：
中科院(CAS)分区：
出版当年[2013]版：
大类|3 区医学
小类|2 区全科医学与补充医学3 区药物化学3 区药学3 区植物科学
最新[2025]版：
大类|2 区医学
小类|1 区全科医学与补充医学1 区药学2 区药物化学2 区植物科学
第一作者：
第一作者单位：[a]Department of Neurosurgery, Second Affiliated Hospital of Nanchang University, Nanchang, 330006, China
通讯作者：
推荐引用方式(GB/T 7714)：
Zhang Y,Xie R.-F,Xiao Q.-G,et al.Hedyotis diffusa Willd extract inhibits the growth of human glioblastoma cells by inducing mitochondrial apoptosis via AKT/ERK pathways[J].Journal of ethnopharmacology.2014,158 Pt A:404-11.doi:10.1016/j.jep.2014.10.017.
APA：
Zhang, Y,Xie, R.-F,Xiao, Q.-G,Li, R,Shen, X.-L&Zhu, X.-G.(2014).Hedyotis diffusa Willd extract inhibits the growth of human glioblastoma cells by inducing mitochondrial apoptosis via AKT/ERK pathways.Journal of ethnopharmacology,158 Pt A,
MLA：
Zhang, Y,et al."Hedyotis diffusa Willd extract inhibits the growth of human glioblastoma cells by inducing mitochondrial apoptosis via AKT/ERK pathways".Journal of ethnopharmacology 158 Pt A.(2014):404-11
