To investigate the feasibility and safety of laparoendoscopic single-site surgery (LESS) using conventional laparoscopic instruments in gynecologic disease by three-channel single port through a transumbilical access. A retrospective analysis of 11 patients who underwent LESS procedure from January 2011 to May 2011 was performed. Clinic data were collected from 11 patients, 5 patients underwent salpingectomy, 3 cases with ovarian cystectomy, 2 cases with adnexectomy and 1 case with laparoscopic assisted vaginal hysterectomy (LAVH). Surgical duration, amount of bleeding and postoperative complications were analyzed. Ten of 11 patients were treated with LESS surgery successfully. One patient who underwent laparoscopic assisted vaginal hysterectomy procedure required two additional 5 mm ports due to severe pelvic adhesion. The operation time was 25-85 minutes. The estimated bleeding amount was 5-80 ml. The scars of operation incision in 10 LESS patients were not obvious. One patient under LAVH showed 2 scars of 0.5 cm on the lower abdomen. There were no postoperative complications in all cases. Laparoendoscopic single-site surgery with conventional laparoscopic instrument on suitable gynecologic conditions is feasible, safe and cosmetic. It is easy to perform and low cost. Further studies are needed to confirm these advantages compared with traditional laparoscopic procedure. © 2016, E-Century Publishing Corporation. All rights reserved.