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Role of memory T cells and perspectives for intervention in organ transplantation

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收录情况： ◇ SCIE

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单位： [1]Institute of Organ Transplantation, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China [2]Key Laboratory of Organ Transplantation, Ministry of Education, Wuhan, China [3]Key Laboratory of Organ Transplantation, Ministry of Public Health, Wuhan, China [4]Institute of Organ Transplantation, Tongji Hospital, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Wuhan 430030, China

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关键词： memory T cells transplantation allograft rejection tolerance therapy

摘要：

Memory T cells are necessary for protective immunity against invading pathogens, especially under conditions of immunosuppression. However, their presence also threatens transplant survival, making transplantation a great challenge. Significant progress has been achieved in recent years in advancing our understanding of the role that memory T cells play in transplantation. This review focuses on the latest advances in our understanding of the involvement of memory T cells in graft rejection and transplant tolerance and discusses potential strategies for targeting memory T cells in order to minimize allograft rejection and optimize clinical outcomes.

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出版当年[2014]版：

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最新[2025]版：

大类 | 2 区医学

小类 | 2 区免疫学

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出版当年[2013]版：

无

最新[2023]版：

Q1 IMMUNOLOGY

影响因子： 5.7 最新[2023版] 6.8 最新五年平均 0 出版当年[2013版] 0 出版当年五年平均 0 出版前一年[2012版]

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第一作者单位： [1]Institute of Organ Transplantation, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China

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通讯机构： [4]Institute of Organ Transplantation, Tongji Hospital, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Wuhan 430030, China

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