The aim of this paper is to observe and explore the application value of thyroid ultrasound, and the method is to make a retrospective analysis of the results of 2018 adults' thyroid ultrasound. The result is that in all lines of thyroid ultrasound examination adults, 624 cases are abnormal through examination, of which 498 cases are thyroid nodule after diagnosis, 94 cases are diffuse goiter, as well as 32 cases of goiter nodules. As a result, a conclusion is given that the application of thyroid ultrasound in adults' health examination can be helpful to the early detection of thyroid diseases in order to take effective treatment measures in a timely manner. Moreover, the application of thyroid ultrasound can rule out the possibility of thyroid carcinoma, and deal with treatment solutions in time so as to improve patients' quality of life as the same time. It is of great significance to the body's health of the patients, thus thyroid ultrasound should be incorporated into the conventional project of adults' health examination. As a result, this paper mainly makes an analysis of the application value of thyroid ultrasound in adults' health examination. The first part of this paper discusses of the materials and methods of thyroid ultrasound in adults' health examination. The second part of this paper discusses the results of thyroid ultrasound samples in adults' health examination. The last part of this paper is discussion of the application of thyroid ultrasound in adults' health examination, and gives a brief conclusion at the same time.