Parkinson's disease (PD) is one of the most common forms of neurodegenerative disease in the elderly population and is typically manifested by motor symptoms and nonmotor symptoms and signs. Nonmotor symptoms, such as sensory symptoms, have been regarded as the significant features of this disease. These symptoms often occur in early stages of PD and influence quality of life. However, researchers suggest that the sensory symptoms of PD are frequently unrecognized by clinicians and remain untreated. The disorders include pain, olfactory disturbance, and visual dysfunction input on the underlying sensory abnormality. This Review focuses on the clinical features, pathophysiological mechanisms, and treatment strategies for sensory symptoms of PD from both clinical studies and basic research, providing a comprehensive overview of the sensory symptoms in PD. (C) 2016 Wiley Periodicals, Inc.
基金:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81502174, 81270865]; National Natural Science Foundation of Wuhan City [2013060501010154]
第一作者单位:[1]Huazhong Univ Sci & Technol,Dept Neurosurg,Tongji Med Coll,Tongji Hosp,1095 Jiefang Ave,Wuhan 430000,Peoples R China
通讯作者:
推荐引用方式(GB/T 7714):
Zhu Mingxin,Li Man,Ye Dawei,et al.Sensory Symptoms in Parkinson's Disease: Clinical Features, Pathophysiology, and Treatment[J].JOURNAL OF NEUROSCIENCE RESEARCH.2016,94(8):685-692.doi:10.1002/jnr.23729.
APA:
Zhu,Mingxin,Li,Man,Ye,Dawei,Jiang,Wei,Lei,Ting&Shu,Kai.(2016).Sensory Symptoms in Parkinson's Disease: Clinical Features, Pathophysiology, and Treatment.JOURNAL OF NEUROSCIENCE RESEARCH,94,(8)
MLA:
Zhu,Mingxin,et al."Sensory Symptoms in Parkinson's Disease: Clinical Features, Pathophysiology, and Treatment".JOURNAL OF NEUROSCIENCE RESEARCH 94..8(2016):685-692