Background: The correlation between impedance cardiography (ICG) and 6 min walk distance (6MWD) in atrial fibrillation (AF) patients remains unknown. Methods: We recruited 49 subjects in the study (21 AF patients and 28 patients without AF) and estimated hemodynamic parameters: cardiac output (CO), stroke volume (SV), stroke volume index (SVI), left stroke work (LSW), left stroke work index (LSWI), stroke systemic vascular resistance (SSVR), stroke systemic vascular resistance index (SSVRI); 6MWD, left ventricle ejection fraction (LVEF), NT-pro brain natriuretic peptide (NT-pro BNP) for the two groups. Results: The AF group have apparently lower CO (2.26 +/- 0.14 VS 4.11 +/- 0.20 L/min, p = 0.039) and distinctly higher SVR (677.60 +/- 69.10 VS 344.41 +/- 22.98 dynes/cm(5), p = 0.001), SSVRI (396.97 +/- 36.80 VS 199.01 +/- 11.72 dynes/cm(5)/m(2), p < 0. 001) than the control group. NT-pro BNP (1409.48 +/- 239.90 VS 332.59 +/- 68.85 pg/ml, p = 0.001) in the AF group was significantly higher than the control group and 6MWD (264.33 +/- 14.55 VS 428.79 +/- 29.98 m, p < 0.001) in the AF group was lower than the control group. There was no significant difference in LVEF between the two groups (62.67 +/- 7.62 % VS 63.93 +/- 5.03 %, p = 0.470). Pearson correlation analysis revealed that CO (R = 0.494, p = 0.023), SV (R = 0.633, p = 0.002), LSW (R = 0.615, p = 0.003) and LSWI (R= 0.491, p = 0.024) significantly correlated positively with 6MWD in AF patients. Conclusions: AF patients had lower cardiac output, shorter 6MWD and higher NT-pro BNP than patients with sinus rhythm. The cardiac output measured by impedance cardiography significantly correlated positively with 6MWD in AF patients.
基金：
National Natural Science Foundation of China [81400255, 81300141]; Scientific and Technological Projects of Hubei [2015CFB624]
第一作者单位：[1]Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Dept Geriatr, Wuhan 430030, Peoples R China
通讯作者：
推荐引用方式(GB/T 7714)：
Ding Ling,Quan Xiao-Qing,Zhang Shu,et al.Correlation between impedance cardiography and 6 min walk distance in atrial fibrillation patients[J].BMC CARDIOVASCULAR DISORDERS.2016,16:doi:10.1186/s12872-016-0297-0.
APA：
Ding, Ling,Quan, Xiao-Qing,Zhang, Shu,Ruan, Lei,Zhang, Le...&Zhou, Hong-Lian.(2016).Correlation between impedance cardiography and 6 min walk distance in atrial fibrillation patients.BMC CARDIOVASCULAR DISORDERS,16,
MLA：
Ding, Ling,et al."Correlation between impedance cardiography and 6 min walk distance in atrial fibrillation patients".BMC CARDIOVASCULAR DISORDERS 16.(2016)
