OBJECTIVE: The present study aimed to investigate the relationship between obesity and mortality in patients with community-acquired pneumonia (CAP) in China. METHODS: In total, 909 patients with CAP were recruited for this study from January 2010 to June 2015. All patients were selected and divided into 4 groups according to their body mass index (BMI) values. All patients' clinical information was recorded. The associations among mortality; BMI; the 30-day, 6-month and 1-year survival rates for different BMI classes; the etiology of pneumonia in each BMI group; and the risk factors for 1-year mortality in CAP patients were analyzed. RESULT: With the exception of the level of C-reactive protein (CRP), no other clinical indexes showed significant differences among the different BMI groups. No significant differences were observed among all groups in terms of the 30-d and 6-month mortality rates (p > 0.05). There was a significantly lower risk of 1-year mortality in the obese group than in the nonobese group, (p < 0.05). Logistic regression analysis showed that there were seven independent risk factors for 1-year mortality in CAP patients, namely, age, cardiovascular disease, cerebrovascular disease, obesity, APACHE II score, level of CRP and CAP severity. CONCLUSION: Compared with nonobese patients with CAP, obese CAP patients may have a lower mortality rate, especially with regard to 1-year mortality, and CRP may be associated with the lower mortality rate in obese individuals than in nonobese individuals.
基金:
Science and Technology Planning Project of Guangdong Province, China [2015A030401070]
第一作者单位:[1]Wuhan Peoples Hosp Dongxihu Dist, Xiehe Hosp Dongxihu Dist, Dept Crit Care Med, Wuhan 430000, Hubei, Peoples R China
通讯作者:
推荐引用方式(GB/T 7714):
Chen Jin,Wang Jia,Jiang Hui,et al.Lower long-term mortality in obese patients with community-acquired pneumonia: possible role of CRP[J].CLINICS.2019,74:doi:10.6061/clinics/2019/e608.
APA:
Chen, Jin,Wang, Jia,Jiang, Hui,Li, Mao-Chun,He, Si-Yuan...&Shen, Dantong.(2019).Lower long-term mortality in obese patients with community-acquired pneumonia: possible role of CRP.CLINICS,74,
MLA:
Chen, Jin,et al."Lower long-term mortality in obese patients with community-acquired pneumonia: possible role of CRP".CLINICS 74.(2019)