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Prevalence of pulmonary hypertension in peritoneal dialysis patients: a meta-analysis

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单位: [1]Wuhan Forth Hosp, Dept Resp Med, Wuhan 430030, Hubei, Peoples R China [2]Huazhong Univ Sci & Technol, Puai Hosp, Tongji Med Coll, Wuhan 430030, Hubei, Peoples R China [3]Wuhan Forth Hosp, Dept Nephrol & Rheumatol, Wuhan 430030, Hubei, Peoples R China [4]Huazhong Univ Sci & Technol, Dept Med Affaires, Liyuan Hosp, Tongji Med Coll, Wuhan 430030, Hubei, Peoples R China [5]Huazhong Univ Sci & Technol, Dept Otolaryngol Head & Neck Surg, Tongji Hosp, Tongji Med Coll, Wuhan 430030, Hubei, Peoples R China
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关键词: Pulmonary hypertension Prevalence Peritoneal dialysis Meta-analysis

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PurposeRecent epidemiological evidence indicates an association between peritoneal dialysis (PD) patients and pulmonary hypertension (PH). However, the true prevalence of PH associated with PD has not been well described. So we conducted a meta-analysis to summarize the point prevalence of PH in adults with PD.MethodsPubMed, EMBASE, the Cochrane Collaboration, and the reference lists of relevant articles were searched to identify eligible studies. We used a random-effect meta-analysis model to estimate the prevalence of PH. We also performed sensitivity analyses and assessments of publishing bias.ResultsFourteen observational studies (n=1483 participants) were included in this meta-analysis. The result of analysis in random-effect model showed that the pooled prevalence was 21% (95% CI 16-28), with significant heterogeneity between these studies (I-2=84%, p<0.01). Sensitivity analysis further demonstrated the results to be robust. Besides, the Egger's test (p=0.287) showed no significant publication bias.ConclusionsPH is highly prevalent in patients with PD. Further studies are encouraged to definitively clarify the relationship between PH and PD.

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出版当年[2018]版:
大类 | 4 区 医学
小类 | 4 区 泌尿学与肾脏学
最新[2025]版:
大类 | 4 区 医学
小类 | 4 区 泌尿学与肾脏学
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出版当年[2017]版:
Q3 UROLOGY & NEPHROLOGY
最新[2023]版:
Q3 UROLOGY & NEPHROLOGY

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第一作者单位: [1]Wuhan Forth Hosp, Dept Resp Med, Wuhan 430030, Hubei, Peoples R China [2]Huazhong Univ Sci & Technol, Puai Hosp, Tongji Med Coll, Wuhan 430030, Hubei, Peoples R China
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通讯机构: [2]Huazhong Univ Sci & Technol, Puai Hosp, Tongji Med Coll, Wuhan 430030, Hubei, Peoples R China [3]Wuhan Forth Hosp, Dept Nephrol & Rheumatol, Wuhan 430030, Hubei, Peoples R China
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