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Nutritional predictors associated with malnutrition in continuous ambulatory peritoneal dialysis patients

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单位: [1]Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Publ Hlth, Dept Nutr & Food Hyg,Hubei Key Lab Food Nutr & Sa, 13 Hangkong Rd, Wuhan 430030, Hubei, Peoples R China [2]Huazhong Univ Sci & Technol, Sch Publ Hlth, Tongji Med Coll, Dept Social Med & Hlth Management, 13 Hangkong Rd, Wuhan 430030, Hubei, Peoples R China [3]Huazhong Univ Sci & Technol, Tongji Hosp, Dept Clin Nutr, Wuhan 430030, Hubei, Peoples R China [4]Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Publ Hlth, Minist Educ Key Lab Environm & Hlth, Wuhan 430030, Peoples R China
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关键词: Chronic kidney disease End-stage renal disease Continuous ambulatory peritoneal dialysis Malnutrition Subjective global assessment

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Background: Currently in China, out of the total dialysis population, approximately 20% represents continuous ambulatory peritoneal dialysis (CAPD) and almost half of CAPD patients was affected by malnutrition. This study aimed to investigate the association between nutritional predictors and malnutrition with 5.1 years of dialysis according to the subjective global assessment (SGA) in continuous ambulatory peritoneal dialysis (CAPD) patients. Methods: A cross-sectional study was conducted from April 2013 to May 2018 and included 70 CAPD patients. The relationship between anthropometric and biochemical parameters with malnutrition was assessed by multiple logistic regression analysis. Results: The prevalence of malnutrition in CAPD patients was 52.9%. Our result revealed a 7.05-fold increased odds of malnutrition for patients with protein equivalent of total nitrogen appearance normalized to body weight (nPNA) < 1.0 g/kg per day (d) versus patients with normal nPNA (confidence interval (CI) 1.33-37.34; p < 0.05). Patients whose normalized protein catabolic rate (nPCR) was <1.2 g/(kg/d) had a significant positive association with malnutrition versus patients with normal nPCR (adjusted odds ratio (OR) 7.99; p < 0.05). Patients with dietary protein intake (DPI) < 1.0 g/(kg/d) had a higher likelihood of malnutrition than those with normal DPI (OR 12.73; p < 0.05). CAPD patients with upper arm circumference (UAC) < 23.2 cm had a high risk of malnutrition versus patients with normal UAC (OR 12.99; p < 0.05). Conclusions: Our study suggested a close association between nPNA, DPI, nPCR, and UAC and malnutrition in CAPD patients. Further studies can be warranted the use of these variables as predictors and a malnutrition consequence among Chinese CAPD patients. (C) 2021 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights reserved.

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出版当年[2020]版:
最新[2025]版:
大类 | 3 区 医学
小类 | 4 区 营养学
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出版当年[2019]版:
最新[2023]版:
Q3 NUTRITION & DIETETICS

影响因子: 最新[2023版] 最新五年平均 出版当年[2019版] 出版当年五年平均 出版前一年[2018版]

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第一作者单位: [1]Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Publ Hlth, Dept Nutr & Food Hyg,Hubei Key Lab Food Nutr & Sa, 13 Hangkong Rd, Wuhan 430030, Hubei, Peoples R China
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通讯机构: [1]Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Publ Hlth, Dept Nutr & Food Hyg,Hubei Key Lab Food Nutr & Sa, 13 Hangkong Rd, Wuhan 430030, Hubei, Peoples R China [4]Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Publ Hlth, Minist Educ Key Lab Environm & Hlth, Wuhan 430030, Peoples R China
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