Objectives This study aimed to evaluate whether patients stratified by age have the same level of benefits after a sacral neuromodulation (SNM) procedure for refractory lower urinary tract dysfunction. Materials and Methods This retrospective study comprised 211 patients with refractory lower urinary tract dysfunction who had been treated with SNM and recruited from multiple medical centers across China. Patients were grouped according to age: <40 (n = 58), 40-64 (n = 94), and > 64 (n = 59) years. Data were compared using voiding diaries and subjective scores pre-operatively, post-implantation of a stage I tined lead, and during a short-term follow-up period postimplantation of a stage II implanted pulse generator. Results In all groups, voiding diary data and subjective scores improved significantly over different periods. Residual urine improved in the 40-64 and > 64-year-old age groups. Quality of life scores improved in the <40-year-old age group. Voiding diary data among age groups varied at baseline; however, average urinary frequency did not differ at the last follow-up. Urgency and sexual life scores differed at baseline and these differences had resolved at the last follow-up. O'Leary-Sant and Pelvic Pain and Urgency/Frequency Symptoms Scale scores did not differ at baseline; however, significant differences were observed at the last follow-up. Conclusions SNM success is unrelated to age, and age alone should not be considered a limiting factor in SNM. For older patients, an overactive bladder appears a better indication for SNM treatment; however, further studies are required to confirm this finding.
基金:
National Key R&D Program of China [2018YFC2002202] Funding Source: Medline
语种:
外文
被引次数:
WOS:
PubmedID:
中科院(CAS)分区:
出版当年[2019]版:
大类|3 区医学
小类|3 区临床神经病学4 区医学:研究与实验
最新[2025]版:
大类|3 区医学
小类|3 区临床神经病学3 区医学:研究与实验
JCR分区:
出版当年[2018]版:
Q2CLINICAL NEUROLOGYQ3MEDICINE, RESEARCH & EXPERIMENTAL
最新[2023]版:
Q2CLINICAL NEUROLOGYQ2MEDICINE, RESEARCH & EXPERIMENTAL
第一作者单位:[1]Beijing Hosp, Dept Urol, Natl Ctr Gerontol, 1 DaHua Rd, Beijing 100730, Peoples R China
通讯作者:
推荐引用方式(GB/T 7714):
Meng Lingfeng,Zhang Wei,Zhang Yaoguang,et al.Analysis of the Correlation Between the Clinical Effect of Sacral Neuromodulation and Patient Age: A Retrospective Multicenter Study in China[J].NEUROMODULATION.2020,23(8):1189-1195.doi:10.1111/ner.13130.
APA:
Meng, Lingfeng,Zhang, Wei,Zhang, Yaoguang,Wang, Jianye,Liao, Limin...&Chen, Qi.(2020).Analysis of the Correlation Between the Clinical Effect of Sacral Neuromodulation and Patient Age: A Retrospective Multicenter Study in China.NEUROMODULATION,23,(8)
MLA:
Meng, Lingfeng,et al."Analysis of the Correlation Between the Clinical Effect of Sacral Neuromodulation and Patient Age: A Retrospective Multicenter Study in China".NEUROMODULATION 23..8(2020):1189-1195