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Analysis of the Correlation Between the Clinical Effect of Sacral Neuromodulation and Patient Age: A Retrospective Multicenter Study in China

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单位: [1]Beijing Hosp, Dept Urol, Natl Ctr Gerontol, 1 DaHua Rd, Beijing 100730, Peoples R China [2]Capital Med Univ, Rehabil Sch, China Rehabil Res Ctr, Dept Urol, Beijing, Peoples R China [3]Huazhong Univ Sci & Technol,Tongji Hosp,Dept Urol,Wuhan,Peoples R China [4]Capital Med Univ, Beijing Chaoyang Hosp, Inst Urol, Dept Urol, Beijing, Peoples R China [5]Nanjing Med Univ, Affiliated Hosp 2, Dept Urol, Nanjing, Peoples R China [6]Xi An Jiao Tong Univ, Affiliated Hosp 2, Dept Urol, Xian, Peoples R China
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关键词: Age clinical efficacy refractory lower urinary tract dysfunction sacral neuromodulation

摘要:
Objectives This study aimed to evaluate whether patients stratified by age have the same level of benefits after a sacral neuromodulation (SNM) procedure for refractory lower urinary tract dysfunction. Materials and Methods This retrospective study comprised 211 patients with refractory lower urinary tract dysfunction who had been treated with SNM and recruited from multiple medical centers across China. Patients were grouped according to age: <40 (n = 58), 40-64 (n = 94), and > 64 (n = 59) years. Data were compared using voiding diaries and subjective scores pre-operatively, post-implantation of a stage I tined lead, and during a short-term follow-up period postimplantation of a stage II implanted pulse generator. Results In all groups, voiding diary data and subjective scores improved significantly over different periods. Residual urine improved in the 40-64 and > 64-year-old age groups. Quality of life scores improved in the <40-year-old age group. Voiding diary data among age groups varied at baseline; however, average urinary frequency did not differ at the last follow-up. Urgency and sexual life scores differed at baseline and these differences had resolved at the last follow-up. O'Leary-Sant and Pelvic Pain and Urgency/Frequency Symptoms Scale scores did not differ at baseline; however, significant differences were observed at the last follow-up. Conclusions SNM success is unrelated to age, and age alone should not be considered a limiting factor in SNM. For older patients, an overactive bladder appears a better indication for SNM treatment; however, further studies are required to confirm this finding.

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出版当年[2019]版:
大类 | 3 区 医学
小类 | 3 区 临床神经病学 4 区 医学:研究与实验
最新[2025]版:
大类 | 3 区 医学
小类 | 3 区 临床神经病学 3 区 医学:研究与实验
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出版当年[2018]版:
Q2 CLINICAL NEUROLOGY Q3 MEDICINE, RESEARCH & EXPERIMENTAL
最新[2023]版:
Q2 CLINICAL NEUROLOGY Q2 MEDICINE, RESEARCH & EXPERIMENTAL

影响因子: 最新[2023版] 最新五年平均 出版当年[2018版] 出版当年五年平均 出版前一年[2017版] 出版后一年[2019版]

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第一作者单位: [1]Beijing Hosp, Dept Urol, Natl Ctr Gerontol, 1 DaHua Rd, Beijing 100730, Peoples R China
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