Tumour metabolism is a major focus of cancer research, and metabolic reprogramming is an important feature of malignant tumours. Serine is an important non-essential amino acid, which is a main resource of one-carbon units in tumours. Cancer cells proliferate more than normal cells and require more serine for proliferation. The cancer-related genes that are involved in serine metabolism also show changes corresponding to metabolic alterations. Here, we reviewed the serine-associated one-carbon metabolism and its potential as a target for anti-tumour therapeutic strategies.
第一作者单位:[1]Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Dept Oncol, Wuhan, Peoples R China
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推荐引用方式(GB/T 7714):
Zhang Jing,Bai Jian,Gong Chen,et al.Serine-associated one-carbon metabolic reprogramming: a new anti-cancer therapeutic strategy[J].FRONTIERS IN ONCOLOGY.2023,13:doi:10.3389/fonc.2023.1184626.
APA:
Zhang, Jing,Bai, Jian,Gong, Chen,Wang, Jianhua,Cheng, Yi...&Xiong, Huihua.(2023).Serine-associated one-carbon metabolic reprogramming: a new anti-cancer therapeutic strategy.FRONTIERS IN ONCOLOGY,13,
MLA:
Zhang, Jing,et al."Serine-associated one-carbon metabolic reprogramming: a new anti-cancer therapeutic strategy".FRONTIERS IN ONCOLOGY 13.(2023)