BackgroundSleep disorders are highly prevalent among breast cancer patients and have a detrimental impact on their quality of life. This study aims to investigate the serial multiple mediating roles of social support and hope in the relationship between anxiety, depression, and sleep quality in breast cancer patients.MethodsA cross-sectional study was conducted in China from October 2021 to February 2022. A total of 315 breast cancer patients were assessed using self-reported questionnaires, including the Pittsburgh Sleep Quality Index (PSQI), Medical Outcomes Study Social Support Survey (MOS-SSS), Herth Hope Index (HHI), and Hospital Anxiety and Depression Scale (HADS). Mediation analysis was performed using the R Statistical Software.ResultsSleep quality exhibited a negative correlation with hope and medical social support (P < 0.01), and a positive correlation with anxiety and depression (P < 0.01). Anxiety and depression accounted for 18.8% and 12.8% of the variance in sleep quality, respectively. Bootstrap analyses of the anxiety-medical social support-hope-sleep quality pathway indicated the presence of direct effects [B = 0.331, 95%CI (0.215, 0.493)] and indirect effects of anxiety on sleep quality mediated solely by medical social support [B = 0.054, 95%CI (0.015, 0.108)] and hope [B = 0.041, 95%CI (0.018, 0.073)], as well as combined effects [B = 0.012, 95%CI (0.004, 0.025)]. Similarly, the depression-medical social support-hope-sleep quality pathway revealed direct effects [B = 0.235, 95%CI (0.104, 0.372)] and indirect effects of depression on sleep quality mediated solely by medical social support [B = 0.078, 95%CI (0.016, 0.150)] and hope [B = 0.049, 95%CI (0.018, 0.086)], as well as combined effects [B = 0.017, 95%CI (0.004, 0.034)].ConclusionsThis research validates the hypothesis that medical social support and hope serve as mediators between anxiety, depression, and sleep quality in breast cancer patients. Interventions targeting anxiety, depression, medical social support, and hope have the potential to effectively enhance sleep quality.
基金：
This study was funded by Shanxi Province 136 Revitalization
Medical Project Construction Funds.
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2022]版：
大类|2 区医学
小类|2 区康复医学3 区卫生保健与服务3 区肿瘤学
最新[2025]版：
大类|3 区医学
小类|2 区康复医学3 区卫生保健与服务3 区肿瘤学
JCR分区：
出版当年[2021]版：
Q1REHABILITATIONQ2HEALTH CARE SCIENCES & SERVICESQ3ONCOLOGY
最新[2023]版：
Q1REHABILITATIONQ2HEALTH CARE SCIENCES & SERVICESQ2ONCOLOGY
第一作者单位：[1]Shanxi Med Univ, Shanxi Bethune Hosp, Tongji Shanxi Hosp, Shanxi Acad Med Sci,Breast Surg Dept,Hosp 3, Taiyuan 030032, Shanxi, Peoples R China
通讯作者：
通讯机构：[3]Shanxi Med Univ, Shanxi Bethune Hosp, Tongji Shanxi Hosp, Shanxi Acad Med Sci,Hosp 3,Nursing Dept, Taiyuan 030032, Shanxi, Peoples R China[4]Huazhong Univ Sci & Technol,Tongji Hosp,Tongji Med Coll,Wuhan 430030,Hubei,Peoples R China
推荐引用方式(GB/T 7714)：
Zhu Wenjuan,Gao Jinnan,Guo Jun,et al.Anxiety, depression, and sleep quality among breast cancer patients in North China: Mediating roles of hope and medical social support[J].SUPPORTIVE CARE IN CANCER.2023,31(9):doi:10.1007/s00520-023-07972-4.
APA：
Zhu, Wenjuan,Gao, Jinnan,Guo, Jun,Wang, Linying&Li, Wanling.(2023).Anxiety, depression, and sleep quality among breast cancer patients in North China: Mediating roles of hope and medical social support.SUPPORTIVE CARE IN CANCER,31,(9)
MLA：
Zhu, Wenjuan,et al."Anxiety, depression, and sleep quality among breast cancer patients in North China: Mediating roles of hope and medical social support".SUPPORTIVE CARE IN CANCER 31..9(2023)
