详情页 - 聚合机构库演示平台

当前位置：首页 > 详情页

Analysis of Expression of Diabetic Nephropathy-Related Protein and Stem Cell Tissue Repair Under Nano Membrane Concentration Technology

文献详情

资源类型：

WOS体系：

收录情况： ◇ SCIE

作者：

单位： [1]Shanxi Med Univ, Shanxi Bethune Hosp, Tongji Shanxi Hosp, Shanxi Acad Med Sci,Hosp 3,Endocrine Dept, Taiyuan 030032, Peoples R China [2]Huazhong Univ Sci & Technol, Tongji Med Coll, Tongji Hosp, Wuhan 430030, Peoples R China [3]Shanxi Univ Chinese Med, Coll Tradit Chinese Med & Food Engn, Taiyuan 030619, Shanxi, Peoples R China [4]Shanxi Med Univ, Hosp 3, Shanxi Bethune Hosp, Shanxi Acad Med Sci,Tongji Shanxi Hosp, Taiyuan 030032, Peoples R China [5]Shanxi Med Univ, Dept Thorac Surg, Shanxi Prov Canc Hosp, Shanxi Hosp,Canc Hosp,Chinese Acad Med Sci,Canc H, Taiyuan 030013, Peoples R China [6]Shanxi Med Univ, Dept Biochem & Mol Biol, Taiyuan 030001, Shanxi, Peoples R China

出处：

DOI：

ISSN：

关键词： Nanomembrane Concentration Technology Diabetes Nephropathy Protein Stem Cell Tissue Repair

摘要：

This study aimed to study protein expression in diabetic nephropathy (DN) rats and stem cell tissue repair based on nanomembrane concentration technology. Based on the polymer porous self-assembled nanomembrane technology, the content of total protein and albumin in the serum of rats in the control and experimental groups were measured. The obtained images were adopted to analyze the expression of cytoplasmic proteins and membrane proteins, and then the mechanism of stem cell tissue repair function was studied. The results showed that at 56 weeks of age, in contrast to control group, the total protein content in the serum of the experimental group evidently decreased. At 36 weeks of age, the cytoplasmic protein samples of diabetic rats in the experimental group were subjected to three two- dimensional protein electrophoresis. It was found that there were about 701 spots in each gel, and the matching rate was about 87.5%. In contrast to control group, 16 cytoplasmic proteins and 23 membrane proteins of the experimental group changed. The results of the differentially expressed protein analysis indicated that the change trends of protein spots. Based on polymer porous self-assembled nano-film technology, the expression of differential proteins in DN rats was analyzed, which would supplement new research assistance to the mechanism of DN.

基金：

语种：

被引次数：

WOS：

中科院(CAS)分区：

出版当年[2021]版：

大类 | 3 区工程技术

小类 | 4 区纳米科技 4 区材料科学：生物材料

最新[2025]版：

无

JCR分区：

出版当年[2020]版：

Q2 MATERIALS SCIENCE, BIOMATERIALS Q3 NANOSCIENCE & NANOTECHNOLOGY

最新[2023]版：

无

影响因子： 0 最新[2023版] 0 最新五年平均 4.099 出版当年[2020版] 3.492 出版当年五年平均 4.483 出版前一年[2019版] 3.641 出版后一年[2021版]

第一作者：

第一作者单位： [1]Shanxi Med Univ, Shanxi Bethune Hosp, Tongji Shanxi Hosp, Shanxi Acad Med Sci,Hosp 3,Endocrine Dept, Taiyuan 030032, Peoples R China [2]Huazhong Univ Sci & Technol, Tongji Med Coll, Tongji Hosp, Wuhan 430030, Peoples R China

通讯作者：

推荐引用方式(GB/T 7714)：

APA：

MLA：

相关文献

[1]Regulation of the Homeostatic Unfolded Protein Response in Diabetic Nephropathy [2]Podocyte Integrin-β3 and Activated Protein C Coordinately Restrict RhoA Signaling and Ameliorate Diabetic Nephropathy [3]Genome-Wide Association Analysis of Protein-Coding Variants in IgA Nephropathy [4]Activated protein C ameliorates diabetic nephropathy by epigenetically inhibiting the redox enzyme p66Shc [5]Fenugreek lactone attenuates palmitate-induced apoptosis and dysfunction in pancreatic β-cells [6]糖尿病肾病患者蛋白质量和质的选择 [7]Fenugreek lactone attenuates palmitate-induced apoptosis and dysfunction in pancreatic beta-cells [8]Identification of primary genes in glomeruli compartment of immunoglobulin A nephropathy by bioinformatic analysis [9]eATP and autoimmune diabetes [10]The delivery of ambulatory diabetes care to children and adolescents with diabetes