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Mesenchymal stem cells for regenerative medicine in central nervous system

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单位： [1]Huazhong Univ Sci & Technol,Tongji Hosp,Tongji Med Coll,Dept Anesthesia,Wuhan,Peoples R China [2]Huazhong Univ Sci & Technol,Tongji Hosp,Tongji Med Coll,Dept Neurosurg,Wuhan,Peoples R China

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关键词： mesenchymal stem cells (MeSH ID D059630) regenerative medicine central nervous system immunomodulation anti-apoptosis

摘要：

Mesenchymal stem cells (MSCs) are multipotent stem cells, whose paracrine and immunomodulatory potential has made them a promising candidate for central nervous system (CNS) regeneration. Numerous studies have demonstrated that MSCs can promote immunomodulation, anti-apoptosis, and axon re-extension, which restore functional neural circuits. The therapeutic effects of MSCs have consequently been evaluated for application in various CNS diseases including spinal cord injury, cerebral ischemia, and neurodegenerative disease. In this review, we will focus on the research works published in the field of mechanisms and therapeutic effects of MSCs in CNS regeneration.

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出版当年[2021]版：

大类 | 3 区医学

小类 | 3 区神经科学

最新[2025]版：

大类 | 3 区医学

小类 | 3 区神经科学

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出版当年[2020]版：

Q2 NEUROSCIENCES

最新[2023]版：

Q2 NEUROSCIENCES

影响因子： 3.2 最新[2023版] 4.3 最新五年平均 4.677 出版当年[2020版] 4.993 出版当年五年平均 3.707 出版前一年[2019版] 5.152 出版后一年[2021版]

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第一作者单位： [1]Huazhong Univ Sci & Technol,Tongji Hosp,Tongji Med Coll,Dept Anesthesia,Wuhan,Peoples R China

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