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Role of exosomes in cellular communication between tumor cells and the tumor microenvironment.

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收录情况： ◇ SCIE

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单位： [1]Department of Clinical Immunology,Tongji Hospital,Tongji Medical College,Huazhong University of Sciences and Technology,Wuhan,Hubei 430000,P.R. China.

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关键词： exosome tumor microenvironment cancer cellular communication

摘要：

Exosomes are nanovesicles secreted by almost all types of cells. They contain RNAs, microRNAs, proteins and other bioactive substances, and can be used as carriers and for communication between cells. They regulate numerous biological processes, such as tumor development, cell proliferation and resistance to chemotherapy. Exosome-mediated communication between tumor cells and the tumor microenvironment (TME) is crucial in the initiation and progression of tumor development. The present review aims to summarize the role of exosomes in mediating the communication between tumor cells and the TME and to suggest the potential use of exosomes as targets for the development of novel therapeutic strategies against cancer.Copyright: © Li et al.

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出版当年[2021]版：

大类 | 4 区医学

小类 | 4 区肿瘤学

最新[2025]版：

大类 | 4 区医学

小类 | 4 区肿瘤学

JCR分区：

出版当年[2020]版：

Q4 ONCOLOGY

最新[2023]版：

Q3 ONCOLOGY

影响因子： 2.5 最新[2023版] 2.4 最新五年平均 2.967 出版当年[2020版] 2.575 出版当年五年平均 2.311 出版前一年[2019版] 3.111 出版后一年[2021版]

第一作者：

第一作者单位： [1]Department of Clinical Immunology,Tongji Hospital,Tongji Medical College,Huazhong University of Sciences and Technology,Wuhan,Hubei 430000,P.R. China. [*1]Department of Clinical Immunology,Tongji Hospital,Tongji Medical College,Huazhong University of Sciences and Technology,1095 Jiefang Avenue,Wuhan,Hubei 430000,P.R. China

通讯机构： [1]Department of Clinical Immunology,Tongji Hospital,Tongji Medical College,Huazhong University of Sciences and Technology,Wuhan,Hubei 430000,P.R. China. [*1]Department of Clinical Immunology,Tongji Hospital,Tongji Medical College,Huazhong University of Sciences and Technology,1095 Jiefang Avenue,Wuhan,Hubei 430000,P.R. China

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