研究单位：[1]Huazhong University of Science and Technology[2]Department of Anaesthesiology,Tongji Hospital of Tongji Medical College,Huazhong University of Science and Technology Wuhan,Hubei,China,430030
研究目的：
Postoperative agitation (hyperactive delirium) is common following major surgery(incidence was about 20% in our pilot study). Dexmedetomidine was related to a reduced delirium rate when comparing with midazolam in many clinical settings. It is not clear if dexmedetomidine is useful on reducing postoperative delirium. The hypothesis of present study: intraoperative application of dexmedetomidine (0.2ug/kg/h) is is effective (50% reduce) than placebo for reducing of early postoperative delirium and increase postoperative quality of recovery within 24 postoperative hours.
