A Study Evaluating Intensive Chemotherapy With or Without Glasdegib or Azacitidine With or Without Glasdegib In Patients With Previously Untreated Acute Myeloid Leukemia (BRIGHT AML1019)
研究单位:[1]Pfizer[2]Tongji Hospital,Tongji Medical College,Huazhong University of Science & Technology/Cancer Center Wuhan,Hubei,China,430030[3]Henan Provincial People's Hospital/Hematology Department Zhengzhou,Henan,China,450003[4]Henan Cancer Hospital Zhengzhou,Henan,China,450008[5]Institute of Hematology and Blood Diseases Hospital,Chinese Academy of Medical Sciences Tianjin,Tianjin,China,300020[6]The First Affiliated Hospital College of Medicine,Zhejiang University Hangzhou,Zhejiang,China,310003
研究目的:
Glasdegib is being studied in combination with azacitidine for the treatment of adult patients with previously untreated acute myeloid leukemia (AML) who are not candidates for intensive induction chemotherapy (Non-intensive AML population).
Glasdegib is being studied in combination with cytarabine and daunorubicin for the treatment of adult patients with previously untreated acute myeloid leukemia (Intensive AML population).