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Study To Compare Avelumab In Combination With Standard of Care Chemoradiotherapy (SoC CRT) Versus SoC CRT for Definitive Treatment In Patients With Locally Advanced Squamous Cell Carcinoma Of The Head And Neck (JAVELIN HEAD AND NECK 100)

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研究单位: [1]Pfizer [2]Union Hospital,Tongji Medical College,Huazhong University of Science and Technology Wuhan,Hubei,China,430022 [3]Tongji Hospital,Tongji Medical College,Huazhong University of Science & Technology/Cancer Center Wuhan,Hubei,China,430030 [4]Xiangya Hospital Central South University/Oncology Department Changsha,Hunan,China,410008 [5]Liaoning Cancer Hospital & Institute Shenyang,Liaoning,China,110042 [6]Fudan University Shanghai Cancer Center Shanghai,Shanghai,China,200032

研究目的:
This is a phase 3 randomized, placebo controlled study to evaluate the safety and anti-tumor activity of Avelumab in combination with standard of care chemoradiation (SoC CRT) versus SoC CRT alone in front-line treatment of patients with locally advanced head and neck cancer.

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