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Precise Stratification of Genetic Risk of Ovarian Function Impairment

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研究单位: [1]Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of science and technology Wuhan, Hubei, China, 430000 [2]Fujian maternal and Child Health Hospital,Fuzhou,Fujian,China [3]Guangdong maternal and Child Health Hospital,Guangzhou,Guangdong,China [4]Guangdong Provincial People's Hospital,Guanzhou,Guangdong,China [5]Shijiazhuang maternity hospital,Shijiazhuang,Hebei,China [6]The Third Affiliated Hospital of Zhengzhou University,Zhengzhou,Henan,China [7]Central South Hospital of Wuhan University,Wuhan,Hubei,China [8]Hubei maternal and Child Health Hospital,Wuhan,Hubei,China [9]Liyuan Hospital Affiliated to Tongji Medical College of Huazhong University of science and technology,Wuhan,Hubei,China [10]People's Hospital of Wuhan University,Wuhan,Hubei,China [11]Xiangyang Central Hospital,Xiangyang,Hubei,China [12]Changsha maternal and Child Health Hospital,Changsha,Hunan,China [13]The First Affiliated Hospital of Suzhou University,Suzhou,Jiangsu,China [14]Jiangxi maternal and Child Health Hospital,Nanchang,Jiangxi,China [15]Northwest women and children's Hospital,Xi'an,Shanxi,China [16]The First Affiliated Hospital of Xi'an Jiaotong University,Xi'an,Shanxi,China [17]Affiliated Hospital of Yunnan University,Kunming,Yunnan,China [18]Hospital of Obstetrics and Gynecology affiliated to Medical College of Zhejiang University,Hangzhou,Zhejiang,China

研究目的:
Aging is a common problem in human society at present. The fertility decline, perimenopausal symptoms and senile diseases caused by ovarian aging seriously affect women's own health, offspring's health, family and social stability, and endanger national population security. Accurate stratification of genetic risk of ovarian aging has practical significance. Early and accurate identification of high-risk groups of premature ovarian aging can help such women to start early protection of ovarian function, preserve fertility to a greater extent, improve fertility quality, and also be conducive to early prevention and treatment of other systemic diseases and prognosis.

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