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PROfiling Based Endometrial Cancer Adjuvant Therapy

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研究单位: [1]Women's Hospital School of Medicine Zhejiang University,Hangzhou,Zhejiang,China,310000 [2]Tongji Hospital, Huazhong University of Science and Technology,Wuhan,Hubei,China [3]Qilu Hospital of Shandong University,Jinan,Shandong,China [4]Peking University Peoples Hospital,Beijing,China [5]Sun Yat-Sen University Cancer Hospital,Guangzhou,China [6]Obstetrics & Gynecology Hospital of Fudan University,Shanghai,China [7]Shanghai First Maternity and Infant Hospital,Shanghai,China

研究目的:
This is a prospective, multicenter, randomized phase III trial among women with endometrioid adenocarcinoma with high-intermediate and intermediate risk features to investigate the role of integrated genomic-pathologic classification to determine if participants should receive no adjuvant therapy, vaginal brachytherapy, external beam radiotherapy or chemo-radiation therapy based on molecular features as compared to standard radiation therapy.

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