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Study of Abiraterone Acetate in Subjects With Metastatic Castration Resistant Prostate Cancer

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研究单位: [1]Chia Tai Tianqing Pharmaceutical Group Co., Ltd. [2]Peking Union Medical College Hospital [3]Peking University First Hospital [4]TongJi medical college of HuaZhong University of Science & Technology Affiliated TongJi Hospital

研究目的:
Abiraterone acetate is an orally effective CYP17 inhibitor, which is metabolized into abiraterone in the body, and its inhibitory activity against CYP17 is 10-30 times that of ketoconazole. Clinical studies have shown that abiraterone acetate can significantly reduce the level of prostate specific antigen (PSA) in PCa patients, and help to reduce tumors, extending the lifespan of patients with advanced PCa for several years, and the toxicity is acceptable.

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