研究单位：[1]Liver Research Center, Beijing Friendship Hospital[2]Peking University People's Hospital[3]Fudan University[4]Tongji Hospital, Tongji Medical College , Huazhong University of Science and Technology
研究目的：
Patients who have completed 2 years follow-up of the past National 12th Five-Year Major Project on Infectious Diseases will receive another 8 years treatment with entecavir (10 years in total). Collect serology, imaging, and other clinical data to evaluate the incidence and mortality of decompensated cirrhosis and hepatocellular carcinoma. Understand the effects of long-term antiviral therapy on HBV-induced liver fibrosis/cirrhosis.
