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A Study of Abemaciclib (LY2835219) in Participants With Breast Cancer

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研究单位： [1]Eli Lilly and Company [2]Wu Han Tongji Hospital Wuhan City, Hubei, China, 430030 [3]Wuhan Union (Xiehe) Hospital Wuhan, Hubei, China, 430022 [4]Hu Bei Cancer Hospital Wuhan, Hubei, China, 430079 [5]Hunan Province Tumor Hospital Changsha, Hunan, China, 410013 [6]Jilin Province Tumor Hospital Chang Chun, Ji Lin, China, 130012 [7]Nanjing Drum Tower Hosp Affiliated Hosp of Nanjing Univ Med Nanjing, Jiangsu, China, 210008 [8]Jiangsu Province Cancer Hospital Nanjing, Jiangsu, China, 210009 [9]Dalian Med. Univ. No 2 Affiliate Hospital Dalian, Liao Ning, China, 116023 [10]Liaoning Cander Hospital&Institute Shenyang, Liaoning, China, 100042 [11]The First Hospital of China Medical University Shenyang, Liaoning, China, 110001 [12]The First Affiliated Hospital with Nanjing Medical Universit Nanjing, Nanjing, China, 210029 [13]First Affiliated Hospital of Medical College, Xi'an Jiaotong Xi'an, Shaanxi, China, 710061 [14]Zhejiang Cancer Hospital Hang Zhou, Zhejiang, China, 310022 [15]Second Affiliate Hospital of Zhejiang Medical University Hangzhou, Zhejiang, China, 310009 [16]Beijing Tumor Hospital Beijing, China, 100142 [17]Shanghai Tumor Hospital Shanghai, China, 200030 [18]Shanghai First People's Hospital Shanghai, China, 200080 [19]Tianjin Medical University Cancer Institute & Hospital Tianjin, China, 300060 [20]Dr. B. L. Kapur Memorial Hospital New Delhi, Delhi, India, 110005 [21]The Gujarat Cancer & Research Institute (GCRI) Ahmedabad, Gujarat, India, 380016 [22]M S Ramaiah Medical College Hospital Bangalore, Karnataka, India, 560054 [23]Healthcare Global Enterprises Limited (HCG) Bangalore, Karnataka, India, 560095 [24]Tata Memorial Hospital Mumbai, Maharashtra, India, 400 012 [25]Jehangir Hospital Pune, Maharashtra, India, 411001 [26]Christian Medical College and Hospital Vellore, Tamil Nadu, India, 632 004

关键词： Hormone Receptor-Positive HER2-Negative CDK4 CDK6

研究目的：

The main purpose of this study is to evaluate the efficacy of the study drug abemaciclib in postmenopausal women with hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) locoregionally recurrent or metastatic breast cancer.