研究单位:[1]Nanfang Hospital of Southern Medical University[2]302 Military Hospital Of China[3]Beijing Ditan Hospita [4]Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology
The purpose of this study is to to prove that the long-term efficacy of strategy of treatment adjustment at W24 according to virological response based on ROADMAP concept is better than standard of care strategy.
To evaluate the off-treatment durability of HBeAg seroconversion in patients who discontinued treatment due to sustained HBeAg seroconversion and HBV DNA<300copies/ml with over 12 months consolidation treatment