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Protocol for assessing auditory brainstem response in mice using a four-channel recording system.

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单位： [1]Department of Otolaryngology-Head and Neck Surgery,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,Hubei 430030,China [2]Department of Otolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China [3]Key Laboratory of Environmental Health, Ministry of Education, Department of Toxicology, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China

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Evaluating auditory sensitivity is critical to hearing research, particularly to that focusing on hearing impairment. Auditory brainstem response recording is frequently used in mice to assess auditory sensitivity and is an approach superior to the traditional techniques. Here, we describe a protocol for recording ABR in mice using four-channel equipment. We detail the procedures of animal preparation, the setup of the ABR recording system, the click- and tone burst-evoked ABR recordings, and data analysis.© 2022 The Author(s).

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最新[2025]版：

大类 | 4 区生物学

小类 | 4 区生化研究方法

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最新[2023]版：

Q4 BIOCHEMICAL RESEARCH METHODS

影响因子： 1.3 最新[2023版] 1.5 最新五年平均 0 出版当年[2020版] 0 出版当年五年平均 0 出版前一年[2019版]

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第一作者单位： [1]Department of Otolaryngology-Head and Neck Surgery,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,Hubei 430030,China

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