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Chronic Rhinosinusitis and COVID-19

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单位: [1]Inst Invest Biomed August Pi i Sunyer, INGENIO, IRCE, Barcelona, Catalonia, Spain [2]Ctr Biomed Invest Resp Dis, Barcelona, Spain [3]Tech Univ Dresden, Dept Otorhinolaryngol, Smell & Taste Clin, Dresden, Germany [4]Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Dept Otolaryngol Head & Neck Surg, Wuhan, Peoples R China [5]Univ Barcelona, Hosp Clin, ENT Dept, Rhinol Unit, Barcelona, Catalonia, Spain [6]Univ Barcelona, Hosp Clin, ENT Dept, Smell Clin, Barcelona, Catalonia, Spain
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关键词: Chronic rhinosinusitis COVID-19 SARS-CoV-2 Olfactory dysfunction Inflammation endotypes Angiotensin converting enzyme 2 Corticosteroids Biologics Olfactory training Telemedicine

摘要:
The COVID-19 pandemic has raised awareness about olfactory dysfunction, although a loss of smell was present in the general population before COVID-19. Chronic rhinosinusitis (CRS) is a common upper airway chronic inflammatory disease that is also one of the most common causes of olfactory dysfunction. It can be classified into different phenotypes (ie, with and without nasal polyps) and endotypes (ie, type 2 and non-type 2 inflammation). However, scientific information regarding CRS within the context of COVID-19 is still scarce. This review focuses on (1) the potential effects of severe acute respiratory syndrome coronavirus 2 infection on CRS symptoms, including a loss of smell, and comorbidities; (2) the pathophysiologic mechanisms involved in the olfactory dysfunction; (3) CRS diagnosis in the context of COVID-19, including telemedicine; (4) the protective hypothesis of CRS in COVID-19; and (5) the efficacy and safety of therapeutic options for CRS within the context of COVID-19. (C) 2022 American Academy of Allergy, Asthma & Immunology

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出版当年[2021]版:
大类 | 1 区 医学
小类 | 1 区 过敏 1 区 免疫学
最新[2025]版:
大类 | 1 区 医学
小类 | 1 区 免疫学 2 区 过敏
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Q1 ALLERGY Q1 IMMUNOLOGY
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Q1 ALLERGY Q1 IMMUNOLOGY

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第一作者单位: [1]Inst Invest Biomed August Pi i Sunyer, INGENIO, IRCE, Barcelona, Catalonia, Spain [2]Ctr Biomed Invest Resp Dis, Barcelona, Spain [*1]Inst Invest Biomed August Pi i Sunyer IDIBAP, IMAPS CELLEX, IRCE, Dept 2B,Rossello 149-153, Barcelona 08036, Catalonia, Spain
通讯作者:
通讯机构: [1]Inst Invest Biomed August Pi i Sunyer, INGENIO, IRCE, Barcelona, Catalonia, Spain [2]Ctr Biomed Invest Resp Dis, Barcelona, Spain [5]Univ Barcelona, Hosp Clin, ENT Dept, Rhinol Unit, Barcelona, Catalonia, Spain [6]Univ Barcelona, Hosp Clin, ENT Dept, Smell Clin, Barcelona, Catalonia, Spain [*1]Inst Invest Biomed August Pi i Sunyer IDIBAP, IMAPS CELLEX, IRCE, Dept 2B,Rossello 149-153, Barcelona 08036, Catalonia, Spain [*2]Hosp Clin Barcelona, ENT Dept, Rhinol Unit, Barcelona 08036, Catalonia, Spain [*3]Hosp Clin Barcelona, ENT Dept, Smell Clin, Barcelona 08036, Catalonia, Spain
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