单位:[1]Capital Med Univ, Beijing Tongren Hosp, Dept Otolaryngol Head & Neck Surg, Beijing, Peoples R China首都医科大学附属北京同仁医院首都医科大学附属同仁医院[2]Beijing Inst Otolaryngol, Beijing Lab Allerg Dis, Beijing, Peoples R China首都医科大学附属北京同仁医院首都医科大学附属同仁医院[3]Beijing Inst Otolaryngol, Beijing Key Lab Nasal Dis, Beijing, Peoples R China首都医科大学附属北京同仁医院首都医科大学附属同仁医院[4]Chinese Acad Med Sci, Res Unit Diag & Treatment Chron Nasal Dis, Beijing, Peoples R China[5]Nanjing Med Univ, Affiliated Hosp 1, Dept Otorhinolaryngol, Nanjing, Peoples R China江苏省人民医院[6]Nanjing Med Univ, Affiliated Hosp 1, Clin Allergy Ctr, Nanjing, Peoples R China江苏省人民医院[7]Nanjing Med Univ, Int Ctr Allergy Res, Nanjing, Peoples R China[8]Fudan Univ, Dept Otolaryngol Head Neck Surg, Eye & ENT Hosp, Shanghai, Peoples R China[9]Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Dept Otolaryngol Head & Neck Surg, Wuhan, Peoples R China耳鼻咽喉-头颈外科华中科技大学同济医学院附属同济医院[10]Sun Yat Sen Univ, Otorhinolaryngol Hosp, Affiliated Hosp 1, Guangzhou, Peoples R China中山大学附属第一医院[11]Capital Med Univ, Sch Basic Med Sci, Dept Immunol, Beijing, Peoples R China[12]Sun Yat Sen Univ, Affiliated Hosp 3, Dept Otorhinolaryngol Head & Neck Surg, Dept Allergy, Guangzhou, Peoples R China中山大学附属第三医院[13]Chinese Acad Med Sci, Res Units New Technol Endoscop Surg Skull Base Tu, Shanghai, Peoples R China[14]Shanxi Med Univ, Dept Otorhinolaryngol Head & Neck Surg, Hosp 2, Taiyuan, Peoples R China[15]Jilin Univ, Dept Otorhinolaryngol Head & Neck Surg, China Japan Union Hosp, Changchun, Peoples R China吉林大学中日联谊医院[16]Sun Yat Sen Univ, Affiliated Hosp 7, Dept Otolaryngol, Shenzhen, Peoples R China深圳医学信息中心中国医学科学院阜外医院深圳医院[17]Capital Med Univ, Beijing Tongren Hosp, Dept Allergy, Beijing, Peoples R China首都医科大学附属北京同仁医院首都医科大学附属同仁医院
Corticosteroids are efficacious in treating chronic rhinosinusitis (CRS), but concerns on the potential side effects remain, especially for long-term usage of systemic corticosteroids. Accumulated evidence shows that transnasal nebulization may be a reasonable solution in balancing both efficacy and safety. However, no consensus or guideline has been formulated on the use of steroid transnasal nebulization in treating CRS. The consensus is achieved through literature review and exchange of Chinese experts in Group of Otorhinolaryngology and Ophthalmology, Chinese Society of Allergy (CSA). This document covers the development, equipment, pharmacological mechanism, and evidence-based efficacy and safety, as well as the special concern of the application of steroid transnasal nebulization during the coronavirus disease (COVID-19) pandemic. The expert consensus clarifies the application of steroid transnasal nebulization in treating CRS and common comorbidities during the perioperative and postoperative periods.
基金:
national natural science foundation of China [81630023, 81970850, 81870698, 82025010]; National Key R & D Program of China [2018YFC0116800]; CAMS Innovation Fund for Medical Sciences (CIFMS) [2019-I2M-5-022, 2021-I2M-CT-B-098]; Program for Changjiang Scholars and Innovative Research Team [IRT13082]; Beijing Municipal Science and Technology Project [Z181100001618002]
第一作者单位:[1]Capital Med Univ, Beijing Tongren Hosp, Dept Otolaryngol Head & Neck Surg, Beijing, Peoples R China[2]Beijing Inst Otolaryngol, Beijing Lab Allerg Dis, Beijing, Peoples R China[3]Beijing Inst Otolaryngol, Beijing Key Lab Nasal Dis, Beijing, Peoples R China[4]Chinese Acad Med Sci, Res Unit Diag & Treatment Chron Nasal Dis, Beijing, Peoples R China
通讯作者:
通讯机构:[1]Capital Med Univ, Beijing Tongren Hosp, Dept Otolaryngol Head & Neck Surg, Beijing, Peoples R China[2]Beijing Inst Otolaryngol, Beijing Lab Allerg Dis, Beijing, Peoples R China[3]Beijing Inst Otolaryngol, Beijing Key Lab Nasal Dis, Beijing, Peoples R China[4]Chinese Acad Med Sci, Res Unit Diag & Treatment Chron Nasal Dis, Beijing, Peoples R China[17]Capital Med Univ, Beijing Tongren Hosp, Dept Allergy, Beijing, Peoples R China[*1]Beijing Tongren Hosp, 1 Dongjiaominxiang, Beijing 100005, Peoples R China
推荐引用方式(GB/T 7714):
Wang Chengshuo,Cheng Lei,Li Huabin,et al.Chinese expert recommendation on transnasal corticosteroid nebulization for the treatment of chronic rhinosinusitis 2021[J].JOURNAL OF THORACIC DISEASE.2021,13(11):6217-6229.doi:10.21037/jtd-21-1142.
APA:
Wang, Chengshuo,Cheng, Lei,Li, Huabin,Liu, Zheng,Lou, Hongfei...&Zhang, Luo.(2021).Chinese expert recommendation on transnasal corticosteroid nebulization for the treatment of chronic rhinosinusitis 2021.JOURNAL OF THORACIC DISEASE,13,(11)
MLA:
Wang, Chengshuo,et al."Chinese expert recommendation on transnasal corticosteroid nebulization for the treatment of chronic rhinosinusitis 2021".JOURNAL OF THORACIC DISEASE 13..11(2021):6217-6229