Carbon monoxide (CO) is one of the endogenous gaseous messengers or gasotransmitters, and is a paramount mediator in physiological and disease conditions. In this review, we focus on the functions of CO in normal and pathological renal physiology. We discuss endogenous renal CO production and signaling in the normal kidney, the characteristic of CO-releasing molecules (CORMs) modalities, and outline its regulatory functions in renal physiology. This article summarizes the mechanisms as well as the effect of CO in the evolving field of renal diseases. We predict numerous innovative CO applications forevolvingcutting-edge scholarly work in the future.
基金：
National Natural Sci-ence Foundation of P.R. China [81800609]
第一作者单位：[1]Huazhong Univ Sci & Technol, Tongji Med Coll, Tongji Hosp, Dept Nephrol, Wuhan, Peoples R China
通讯作者：
推荐引用方式(GB/T 7714)：
Liu Qingquan,Cheng Anying,Wang Yiru,et al.Carbon Monoxide in Renal Physiology, Pathogenesis and Treatment of Renal Disease[J].CURRENT PHARMACEUTICAL DESIGN.2021,27(41):4253-4260.doi:10.2174/1381612827666210706161207.
APA：
Liu, Qingquan,Cheng, Anying,Wang, Yiru,Lv, Yongman&Chen, Zhi.(2021).Carbon Monoxide in Renal Physiology, Pathogenesis and Treatment of Renal Disease.CURRENT PHARMACEUTICAL DESIGN,27,(41)
MLA：
Liu, Qingquan,et al."Carbon Monoxide in Renal Physiology, Pathogenesis and Treatment of Renal Disease".CURRENT PHARMACEUTICAL DESIGN 27..41(2021):4253-4260
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