Hepatocellular carcinoma (HCC) is a typical inflammation-induced cancer and displays a complex interaction between the tumor microenvironment and tumor development. Immune cells in the HCC microenvironment play both pro- and anti-tumoral roles in HCC progression. An increasing number of findings indicate that metabolic reprogramming is essential for immune cell differentiation and function. In this review, we discuss the metabolic changes of different immune cells and correlate these findings to HCC progression.
基金：
National Institute of Health [R01-GM95566, R01-CA214865-02]; National Natural Science Foundation of China [81700515]
第一作者单位：[1]Ohio State Univ, Dept Surg, Div Surg Oncol, Wexner Med Ctr, Columbus, OH 43210 USA[2]Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Dept Gastroenterol, Wuhan, Hubei, Peoples R China
通讯作者：
通讯机构：[1]Ohio State Univ, Dept Surg, Div Surg Oncol, Wexner Med Ctr, Columbus, OH 43210 USA[*1]Ohio State Univ, Div Surg Oncol, Wexner Med Ctr, 410 W 10th Ave,N-924 Doan Hall, Columbus, OH 43210 USA
推荐引用方式(GB/T 7714)：
Xia Yujia,Brown Zachary J.,Huang Hai,et al.Metabolic reprogramming of immune cells: Shaping the tumor microenvironment in hepatocellular carcinoma[J].CANCER MEDICINE.2021,10(18):6374-6383.doi:10.1002/cam4.4177.
APA：
Xia, Yujia,Brown, Zachary J.,Huang, Hai&Tsung, Allan.(2021).Metabolic reprogramming of immune cells: Shaping the tumor microenvironment in hepatocellular carcinoma.CANCER MEDICINE,10,(18)
MLA：
Xia, Yujia,et al."Metabolic reprogramming of immune cells: Shaping the tumor microenvironment in hepatocellular carcinoma".CANCER MEDICINE 10..18(2021):6374-6383
