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CLINICAL CHARACTERISTICS OF DEATH AND RECOVERED CASES OF COVID-19 PATIENTS WITH ENDOTRACHEAL INTUBATION

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单位: [1]Huazhong Univ Sci & Technol, Tongji Med Coll, Tongji Hosp, Dept Resp & Crit Care Med, 1095 Jiefang Ave, Wuhan 430030, Hubei, Peoples R China [2]Wuhan Univ, Renmin Hosp, Dept Resp & Crit Care Med, Wuhan 430060, Hubei, Peoples R China
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关键词: COVID-19 endotracheal intubation death recovery

摘要:
Introduction: To investigate the clinical characteristics of endotracheal coronavirus disease 2019 (COVID-19) andfactors related to death or recovery. Materials and inethods. A total of 126 patients diagnosed with COV1D-19 with endotracheal intubation were included in tl!is study. Personal information, laboratory tests, imaging studies, and clini_cia9.1 data were collected to.analyze.. the clinical characteristics. of endotracheal intubation patients who died or recoveredfrom C(?1/II) Results: 1. A significantly higher propiirtion of patients in the death group received antibiotic therapy and.glucoco.rticoid dosage than those in the recovery group (P<0.05). The time from admission to intubation and comPlictitions after intubatiotiwas significantly longer in the death,group than in the recovery group (P<0.05). The ProPortion of use Extracorporeal MembraneOlgxyngenation(EC,M0) was significantly lower in the. death group than in the recovery group (P<0.05). 2. The patients in 3the death group older, and a significantly htgher proportion of the patients in the death group than in the recovery group wereinen orwwereerselgsmritfiokcearrisil(YP<0.05). The comorftidities anti. proportion Post-intubation Infection was significantly higher in the death group than in the recovery group (P<0.05). in admission time was significantly earlier in the death group than. in the recovery group 0 05). 3. /her was more pronounced in the death group in terms of both the proportion of patients with. this sympt.om and its(sPev<er; (P<0.05). The blood oxygen saturation level was significantly lower.and the respirator)) rate was significant.ly higher in they death group than in the recovery group (P<0:05). 4. Pretreatment (at admission) white blood cells, netitrophils, 1) -dieters, aspartate aminotran.)ferase, procalcitoniti, and C-reactive protein and posttreatment white ft pblood cells, neutropils, as. artate aminotramferase, creatinine, erythrocyte sedimentation rate, procalcitonln, andC-reactive protein were significantly higher in the death group than in the recovery group (P<0.05). Pretreatment lymphocytes, albumin, andoxygen partial pressure and posttreatment albumin antioxygenpartialpressurewere significantly lower in the death group than in the recovery group (P<0.05). Laboratory tests showed that in the recovery group, white blood cells, lymphocytes,.rteittrophils, and platelets were significantly increased after treatment, and as.partate atninotransferase and C-reactive protein were significantly clecTeased after treatment (P<0.05). Whyte blood cells, neutrophils, BNP and plate also significantly incre.aseci.after treatment in the death group (P<0.0.5). Conclusion:letsweeAdvanced age, smoking, high fever,. time from atintission to intubation, EC1110, complications and infection after intubation, rapid respiratory rate, low oxygen saturation are adverse prognostic factors.

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大类 | 4 区 医学
小类 | 4 区 医学:内科
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Q4 MEDICINE, GENERAL & INTERNAL
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第一作者单位: [1]Huazhong Univ Sci & Technol, Tongji Med Coll, Tongji Hosp, Dept Resp & Crit Care Med, 1095 Jiefang Ave, Wuhan 430030, Hubei, Peoples R China
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