Alzheimer's disease is an age-dependent neurodegenerative disease. Recently, di?ferent non-coding RNAs (ncRNAs), including microRNAs, long non-coding RNAs, and circular RNAs, have been found to contribute to Alzheimer's disease's pathogenesis. Extracellular vehicles could be enriched in ncRNAs and in their role in mediating intercellular communication. Signatures of extracellular vesicular ncRNAs have shown them to be a potential biomarker in Alzheimer's disease. This perspective discusses the potential role of extracellular vehicle ncRNAs in Alzheimer's disease, providing a theoretical basis for extracellular vesicular ncRNAs in Alzheimer's disease, from pathogenesis to diagnosis and treatment.
基金:
National Natural Science Foundation of China [81801069, 81500925]
第一作者单位:[1]Southern Med Univ, Shenzhen Baoan Hosp, Dept Clin Lab, Shenzhen 518000, Peoples R China
通讯作者:
推荐引用方式(GB/T 7714):
Xu Yu-Zhong,Cheng Ming-Gang,Wang Xiong,et al.The emerging role of non-coding RNAs from extracellular vesicles in Alzheimer's disease[J].JOURNAL OF INTEGRATIVE NEUROSCIENCE.2021,20(1):239-245.doi:10.31083/j.jin.2021.01.360.
APA:
Xu, Yu-Zhong,Cheng, Ming-Gang,Wang, Xiong&Hu, Yu.(2021).The emerging role of non-coding RNAs from extracellular vesicles in Alzheimer's disease.JOURNAL OF INTEGRATIVE NEUROSCIENCE,20,(1)
MLA:
Xu, Yu-Zhong,et al."The emerging role of non-coding RNAs from extracellular vesicles in Alzheimer's disease".JOURNAL OF INTEGRATIVE NEUROSCIENCE 20..1(2021):239-245