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The emerging role of non-coding RNAs from extracellular vesicles in Alzheimer's disease

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单位: [1]Southern Med Univ, Shenzhen Baoan Hosp, Dept Clin Lab, Shenzhen 518000, Peoples R China [2]Huazhong Univ Sci & Technol,Tongji Hosp,Tongji Med Coll,Dept Lab Med,Wuhan 430030,Peoples R China [3]Huazhong Univ Sci & Technol,Tongji Hosp,Inst Pathol,Tongji Med Coll,Wuhan 430030,Peoples R China
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关键词: Alzheimer' s disease Non-coding RNA Extracellular vesicle Exosome

摘要:
Alzheimer's disease is an age-dependent neurodegenerative disease. Recently, di?ferent non-coding RNAs (ncRNAs), including microRNAs, long non-coding RNAs, and circular RNAs, have been found to contribute to Alzheimer's disease's pathogenesis. Extracellular vehicles could be enriched in ncRNAs and in their role in mediating intercellular communication. Signatures of extracellular vesicular ncRNAs have shown them to be a potential biomarker in Alzheimer's disease. This perspective discusses the potential role of extracellular vehicle ncRNAs in Alzheimer's disease, providing a theoretical basis for extracellular vesicular ncRNAs in Alzheimer's disease, from pathogenesis to diagnosis and treatment.

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出版当年[2020]版:
大类 | 4 区 医学
小类 | 4 区 神经科学
最新[2025]版:
大类 | 3 区 医学
小类 | 3 区 神经科学
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出版当年[2019]版:
Q4 NEUROSCIENCES
最新[2023]版:
Q3 NEUROSCIENCES

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第一作者单位: [1]Southern Med Univ, Shenzhen Baoan Hosp, Dept Clin Lab, Shenzhen 518000, Peoples R China
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