Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2, has posed a serious threat to global public health security. With the increase in the number of confirmed cases globally, the World Health Organization has declared the outbreak of COVID-19 an international public health emergency. Despite atypical pneumonia as the primary symptom, liver dysfunction has also been observed in many clinical cases and is associated with the mortality risk in patients with COVID-19, like severe acute respiratory syndrome and Middle East respiratory syndrome. Here we will provide a schematic overview of the clinical characteristics and the possible mechanisms of liver injury caused by severe acute respiratory syndrome coronavirus 2 infection, which may provide help for optimizing the management of liver injury and reducing mortality in COVID-19 patients.
基金:
National Major Science and Technology Special Project on Major New Drug Innovation [2018ZX09733001-002-006]; Natural Science Foundation of Hubei Province [2019CFB328]
第一作者单位:[1]Huazhong Univ Sci & Technol,Tongji Hosp,Tongji Med Coll,Inst Infect Dis,1095 Jiefang Dadao,Wuhan 430030,Hubei,Peoples R China
通讯作者:
推荐引用方式(GB/T 7714):
Han Mei-Wen,Wang Ming,Xu Meng-Ying,et al.Clinical features and potential mechanism of coronavirus disease 2019-associated liver injury[J].WORLD JOURNAL OF CLINICAL CASES.2021,9(3):doi:10.12998/wjcc.v9.i3.528.
APA:
Han, Mei-Wen,Wang, Ming,Xu, Meng-Ying,Qi, Wei-Peng,Wang, Peng&Xi, Dong.(2021).Clinical features and potential mechanism of coronavirus disease 2019-associated liver injury.WORLD JOURNAL OF CLINICAL CASES,9,(3)
MLA:
Han, Mei-Wen,et al."Clinical features and potential mechanism of coronavirus disease 2019-associated liver injury".WORLD JOURNAL OF CLINICAL CASES 9..3(2021)