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Clinical features and potential mechanism of coronavirus disease 2019-associated liver injury

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单位: [1]Huazhong Univ Sci & Technol,Tongji Hosp,Tongji Med Coll,Inst Infect Dis,1095 Jiefang Dadao,Wuhan 430030,Hubei,Peoples R China
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关键词: COVID-19 Novel coronavirus SARS-CoV-2 Liver injury

摘要:
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2, has posed a serious threat to global public health security. With the increase in the number of confirmed cases globally, the World Health Organization has declared the outbreak of COVID-19 an international public health emergency. Despite atypical pneumonia as the primary symptom, liver dysfunction has also been observed in many clinical cases and is associated with the mortality risk in patients with COVID-19, like severe acute respiratory syndrome and Middle East respiratory syndrome. Here we will provide a schematic overview of the clinical characteristics and the possible mechanisms of liver injury caused by severe acute respiratory syndrome coronavirus 2 infection, which may provide help for optimizing the management of liver injury and reducing mortality in COVID-19 patients.

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出版当年[2020]版
大类 | 4 区 医学
小类 | 4 区 医学:内科
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Q3 MEDICINE, GENERAL & INTERNAL
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Q3 MEDICINE, GENERAL & INTERNAL

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第一作者单位: [1]Huazhong Univ Sci & Technol,Tongji Hosp,Tongji Med Coll,Inst Infect Dis,1095 Jiefang Dadao,Wuhan 430030,Hubei,Peoples R China
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