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Post-lockdown SARS-CoV-2 nucleic acid screening in nearly ten million residents of Wuhan, China

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单位: [1]Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Publ Hlth, Dept Social Med & Hlth Management, Wuhan, Hubei, Peoples R China [2]Univ East Anglia, Fac Med & Hlth Sci, Norwich Med Sch, Norwich, Norfolk, England [3]Wuhan Municipal Hlth Commiss, Wuhan, Hubei, Peoples R China [4]Wuhan Ctr Clin Lab, Wuhan, Hubei, Peoples R China [5]Jiangxi Sci & Technol Normal Univ, Sch Econ & Management, Dept Management Sci & Engn, Nanchang, Jiangxi, Peoples R China [6]Huazhong Univ Sci & Technol, Tongji Hosp, Wuhan, Hubei, Peoples R China [7]La Trobe Univ, Sch Psychol & Publ Hlth, Ctr Alcohol Policy Res, Melbourne, Vic, Australia [8]Univ Melbourne, Melbourne Sch Populat & Global Hlth, Melbourne, Vic, Australia [9]Zhengzhou Univ, Sch Publ Hlth, Zhengzhou, Henan, Peoples R China [10]Hainan Med Univ, Affiliated Hosp 2, Hainan Clin Res Ctr Acute & Crit Dis, Dept Emergency, Haikou, Hainan, Peoples R China
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Stringent COVID-19 control measures were imposed in Wuhan between January 23 and April 8, 2020. Estimates of the prevalence of infection following the release of restrictions could inform post-lockdown pandemic management. Here, we describe a city-wide SARS-CoV-2 nucleic acid screening programme between May 14 and June 1, 2020 in Wuhan. All city residents aged six years or older were eligible and 9,899,828 (92.9%) participated. No new symptomatic cases and 300 asymptomatic cases (detection rate 0.303/10,000, 95% CI 0.270-0.339/10,000) were identified. There were no positive tests amongst 1,174 close contacts of asymptomatic cases. 107 of 34,424 previously recovered COVID-19 patients tested positive again (re-positive rate 0.31%, 95% CI 0.423-0.574%). The prevalence of SARS-CoV-2 infection in Wuhan was therefore very low five to eight weeks after the end of lockdown. Large-scale population screening can provide insights to levels of ongoing SARS-CoV-2 transmission. Here, the authors report a citywide screening of similar to 10,000,000 residents of Wuhan and show that SARS-CoV-2 infection prevalence was very low five to eight weeks after the end of lockdown.

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大类 | 1 区 综合性期刊
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大类 | 1 区 综合性期刊
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Q1 MULTIDISCIPLINARY SCIENCES
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Q1 MULTIDISCIPLINARY SCIENCES

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第一作者单位: [1]Huazhong Univ Sci & Technol, Tongji Med Coll, Sch Publ Hlth, Dept Social Med & Hlth Management, Wuhan, Hubei, Peoples R China
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