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Slow Recovery from Critical Coronavirus Disease 2019 Pneumonia in an Immunosuppressed Renal Transplant Recipient with Early Acute Cardiorenal Syndrome

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单位: [1]Huazhong Univ Sci & Technol, Inst Organ Transplantat, Tongji Hosp, Tongji Med Coll, Wuhan, Peoples R China [2]Chinese Acad Med Sci, Key Lab Organ Transplantat, Minist Educ, Minist Publ Hlth, Wuhan, Peoples R China [3]Huazhong Univ Sci & Technol, Dept Radiol, Tongji Hosp, Tongji Med Coll, Wuhan, Peoples R China [4]Huazhong Univ Sci & Technol, Dept Lab Med, Tongji Hosp, Tongji Med Coll, Wuhan, Peoples R China [5]Wuhan Univ, Dept Organ Transplantat, Renmin Hosp, Jiefang Rd 238, Wuhan 430060, Peoples R China
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关键词: COVID-19 Renal transplantation Cardiorenal syndrome Virus shedding Immunosuppression

摘要:
With the global spread of SARS-Cov-2 infections, increasing numbers of COVID-19 cases have been reported in transplant recipients. However, reports are lacking concerning the treatment and prognosis of COVID-19 pneumonia in renal transplant recipients with acute cardiorenal syndrome. We report here the complete clinical course of a renal transplant recipient with critical COVID-19 pneumonia. In the early phase of SARS-Cov-2 infection, the patient exhibited extensive lung lesions and significant acute kidney and heart injuries, which required treatment in the ICU. After correcting the arrhythmia and heart failure, the patient recovered quickly from the acute kidney injury with a treatment of intensive diuresis and strict control of fluid intake. Without cessation of oral immunosuppressive agents, the patient presented a delayed and low antibody response against SARS-Cov-2 and reappeared positive for the virus twice after being discharged. Nevertheless, the patient's pneumonia continued to improve and he fully recovered in 69 days. This effectively treated case may be meaningful and referable for the treatment of COVID-19 pneumonia in other transplant recipients with acute cardiorenal syndrome.

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出版当年[2019]版:
大类 | 4 区 医学
小类 | 3 区 泌尿学与肾脏学 4 区 心脏和心血管系统
最新[2025]版:
大类 | 3 区 医学
小类 | 4 区 心脏和心血管系统 4 区 泌尿学与肾脏学
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出版当年[2018]版:
Q2 UROLOGY & NEPHROLOGY Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
最新[2023]版:
Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Q2 UROLOGY & NEPHROLOGY

影响因子: 最新[2023版] 最新五年平均 出版当年[2018版] 出版当年五年平均 出版前一年[2017版] 出版后一年[2019版]

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第一作者单位: [1]Huazhong Univ Sci & Technol, Inst Organ Transplantat, Tongji Hosp, Tongji Med Coll, Wuhan, Peoples R China [2]Chinese Acad Med Sci, Key Lab Organ Transplantat, Minist Educ, Minist Publ Hlth, Wuhan, Peoples R China
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通讯机构: [1]Huazhong Univ Sci & Technol, Inst Organ Transplantat, Tongji Hosp, Tongji Med Coll, Wuhan, Peoples R China [*1]Tongji Hosp, Inst Organ Transplantat, Jiefang Ave 1095, Wuhan 430060, Peoples R China
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