Purpose: There is increasing evidence indicating that considerable fractions of cases of SARS-CoV-2 infection are asymptomatic. We traced three asymptomatic clusters to investigate the infectivity of subclinical cases of coronavirus disease 2019 (COVID-19). Patients and Methods: Three medical staff who were asymptomatic were diagnosed with coronavirus disease 2019 by serological tests. Their close contacts were systematically evaluated based on COVID-19-related symptoms, nucleic acid tests, serological tests, and chest computed tomography (CT) as needed to determine if they were infected by SARS-CoV-2. Results: None of the staff's close contacts, including 10 family members, were infected by the indexes, even though no protective measures were taken. Conclusion: The infectivity of asymptomatic subclinical infection patients of coronavirus disease 2019 seems to be low.
基金：
Emergency Research Project of Tongji hospital of Huazhong University of Science and Technology [2020kfyXGYJ045]
第一作者单位：[1]Huazhong Univ Sci & Technol,Tongji Hosp,Tongji Med Coll,Dept Ophthalmol,Wuhan 430030,Hubei,Peoples R China
通讯作者：
推荐引用方式(GB/T 7714)：
Zhang Xian,Chen Liting,Wei Jia,et al.Asymptomatic Subclinical Cases of Coronavirus Disease 2019 without Viral Transmission in Three Independent Families[J].INFECTION AND DRUG RESISTANCE.2020,13:3267-3271.doi:10.2147/IDR.S261304.
APA：
Zhang, Xian,Chen, Liting,Wei, Jia,Zhou, Jianfeng,Cao, Yang&Wang, Gaoxiang.(2020).Asymptomatic Subclinical Cases of Coronavirus Disease 2019 without Viral Transmission in Three Independent Families.INFECTION AND DRUG RESISTANCE,13,
MLA：
Zhang, Xian,et al."Asymptomatic Subclinical Cases of Coronavirus Disease 2019 without Viral Transmission in Three Independent Families".INFECTION AND DRUG RESISTANCE 13.(2020):3267-3271
