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Impact of Metabolic Syndrome on Ablation-Outcome in Patients with Atrial Fibrillation: A Systematic Review.

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单位： [1]St. David?s Medical Center, Texas Cardiac Arrhythmia Institute, Austin, Texas. [2]School of Biological Sciences, University of Texas at Austin, Texas. [3]Department of Biomedical Engineering, University of Texas at Austin, Texas. [4]Department of Cardiology, University of Foggia, Foggia, Italy. [5]Department of Internal Medicine, Tong-Ji Hospital, Tong-Ji Medical College, Huazhong University of Science and Technology, Wuhan, China. [6]Division of Cardiology, Stanford University, Palo Alto, California. [7]Interventional Electrophysiology, Scripps Clinic, San Diego, California.

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Metabolic syndrome (MS), a pro-inflammatory state with hypertension, diabetes, dyslipidemia and obesity is presumed to be a close associate of atrial fibrillation (AF). However, the exact mechanism by which MS facilitates perpetuation of AF is yet to be fully understood. Moreover, the impact of the components of MS as well as MS as a group, on ablation-outcome in AF is not clearly elucidated until now. This review has compiled the results from major studies that have looked into those risk factors and defined their significance in influencing ablation-outcome in AF. It has also overviewed the impact of life-style changes that might improve the success rate of AF-ablation by effectively addressing the different constituents of MS.

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第一作者单位： [1]St. David?s Medical Center, Texas Cardiac Arrhythmia Institute, Austin, Texas. [2]School of Biological Sciences, University of Texas at Austin, Texas.

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