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Stem Cell Therapy for Necrotizing Enterocolitis: Innovative Techniques and Procedures for Pediatric Translational Research

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单位: [1]Huazhong Univ Sci & Technol,Tongji Hosp,Tongji Med Coll,Dept Pediat Surg,Wuhan 430074,Peoples R China [2]Huazhong Univ Sci & Technol, Wuhan Puai Hosp, Tongji Med Coll, Dept Cardiovasc & Resp Med, Wuhan 430074, Peoples R China [3]Ohio State Univ, Coll Med, Nationwide Childrens Hosp, Dept Pediat Surg,Ctr Perinatal Res,Res Inst, Columbus, OH 43210 USA
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关键词: Necrotizing enterocolitis Mesenchymal stem cells Transplantation Intravenous injection

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Necrotizing enterocolitis (NEC) is the most common gastrointestinal emergency of newborns, especially those born prematurely. Mesenchymal stem cell (MSC) therapy has shown efficacy in protection against various forms of tissue injury, and we have demonstrated efficacy in experimental NEC. However, few studies have been performed to establish a safe and effective method of intravenous MSC infusion for newborns. Here we described a safe, non-traumatic, and effective technique for systemic MSC transplantation in newborn rats.

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第一作者单位: [1]Huazhong Univ Sci & Technol,Tongji Hosp,Tongji Med Coll,Dept Pediat Surg,Wuhan 430074,Peoples R China
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