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Outcome of a Solitary Kidney Transplant Into Adult Recipients From Pediatric Donors After Controlled Circulatory Death

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单位: [1]Changzheng Hosp, Dept Organ Transplantat, Shanghai 200003, Peoples R China [2]Red Cross Org, Organ Donat Working Grp, Shenzhen, Peoples R China [3]Tongji Hosp,Inst Organ Transplantat,Wuhan 430030,Peoples R China
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关键词: Renal transplantation Deceased pediatric donor Solitary graft Survival Vascular complication

摘要:
Objectives: We sought to evaluate the outcomes of a single kidney transplant from pediatric donors into adult recipients after controlled circulatory death. Materials and Methods: A retrospective, single-center review of all adult recipients who received a single pediatric kidney from controlled-cardiac deceased-donors (aged, < 9 years old) between January 2006 and March 2008 was performed. Results: Eleven adult recipients (aged, 16-41 years) used single renal grafts from the controlled-cardiac deceased-donors (median donor age, 74 months; range, 49-106 months; median donor weight, 20.95 kg; range, 16.6-37.8 kg). The median recipient age was 27 years (range, 16-41 years; median recipient weight, 47 kg; range 39.5-53.6 kg). The patient's serum creatinine level gradually decreased, and the estimated glomerular filtration rate increased stably more than 2 times during follow-up. The graft length increased significantly the first week after transplant compared with that recorded immediately after reperfusion (P < .001) and grew slightly thereafter. Acute rejection occurred in 1 patient. Nine patients had high renal artery blood flow velocity index at 1 to 2 cm. Beside the anastomosis (167-321 cm/s), only 1 patient developed hypertension and slightly increased serum creatinine at 14 weeks after transplant. The 1-year patient/graft survival was 100%. Conclusions: Use of single kidneys from pediatric donors after controlled cardiac death could expand the donor pool without compromising recipient outcomes.

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出版当年[2010]版:
大类 | 4 区 医学
小类 | 4 区 移植
最新[2025]版:
大类 | 4 区 医学
小类 | 4 区 移植
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出版当年[2009]版:
Q4 TRANSPLANTATION
最新[2023]版:
Q4 TRANSPLANTATION

影响因子: 最新[2023版] 最新五年平均 出版当年[2009版] 出版当年五年平均 出版前一年[2008版] 出版后一年[2010版]

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第一作者单位: [1]Changzheng Hosp, Dept Organ Transplantat, Shanghai 200003, Peoples R China
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通讯机构: [1]Changzheng Hosp, Dept Organ Transplantat, Shanghai 200003, Peoples R China [*1]Changzheng Hosp, Dept Organ Transplantat, 415 Fengyang Rd, Shanghai 200003, Peoples R China
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