单位：[1]Department of Obstetrics and Gynecology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,China华中科技大学同济医学院附属同济医院妇产科教研室妇产科学系[2]Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing[3]Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China华中科技大学同济医学院附属协和医院[4]Department of Gynecologic Neoplasms,Hunan Province Tumor Hospital, The Affiliated Tumor Hospital of Central South University, Changsha[5]The First Affiliated Hospital, Medical School of Xi’an Jiaotong University, Xi’an[6]Department of Gynecologic Oncology,The Second Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong[7]Xiangyang Central Hospital,First Affiliated Hospital of Hubei University of Arts and Science. Xiangyang, Hubei[8]Tianjin Central Hospital for Gynecology and Obstetrics, Tianjin[9]Zhong Nan Hospital, Wuhan University,Wuhan[10]Commercial Vocational Hospital, Wuhan[11]The First Affiliated Hospital of Henan University of Science and Technology, Luoyang, Henan[12]Department of Obstetrics and Gynecology,The Central Hospital of Wuhan, Wuhan[13]Shenzhen People’s Hospital, the Second Clinical Hospital of Jinan University, Shenzhen深圳市人民医院深圳医学信息中心[14]Women’s Reproductive Health Laboratory of Zhejiang Province, Zhejiang, China浙江大学医学院附属妇产科医院[15]Department Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing
Background: This study aimed to establish a nomogram by combining clinicopathologic factors with overall survival of stage IA-IIB cervical cancer patients after complete resection with pelvic lymphadenectomy. Materials and Methods: This nomogram was based on a retrospective study on 1,563 stage IA-IIB cervical cancer patients who underwent complete resection and lymphadenectomy from 2002 to 2008. The nomogram was constructed based on multivariate analysis using Cox proportional hazard regression. The accuracy and discriminative ability of the nomogram were measured by concordance index (C-index) and calibration curve. Results: Multivariate analysis identified lymph node metastasis (LNM), lymph-vascular space invasion (LVSI), stromal invasion, parametrial invasion, tumor diameter and histology as independent prognostic factors associated with cervical cancer survival. These factors were selected for construction of the nomogram. The C-index of the nomogram was 0.71 (95% CI, 0.65 to 0.77), and calibration of the nomogram showed good agreement between the 5-year predicted survival and the actual observation. Conclusions: We developed a nomogram predicting 5-year overall survival of surgically treated stage IA-IIB cervical cancer patients. More comprehensive information that is provided by this nomogram could provide further insight into personalized therapy selection.
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外文
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出版当年[2014]版：
大类|4 区医学
小类|4 区肿瘤学
最新[2025]版：
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第一作者：
第一作者单位：[1]Department of Obstetrics and Gynecology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,China[2]Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing
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推荐引用方式(GB/T 7714)：
Hang Zhou,Xiong Li,Yuan Zhang,et al.Establishing a nomogram for stage IA-IIB cervical cancer patients after complete resection[J].Asian Pacific journal of cancer prevention : APJCP.2015,16(9):3773-7.doi:10.7314/APJCP.2015.16.9.3773.
APA：
Hang Zhou,Xiong Li,Yuan Zhang,Yao Jia,Ting Hu...&Shuang Li.(2015).Establishing a nomogram for stage IA-IIB cervical cancer patients after complete resection.Asian Pacific journal of cancer prevention : APJCP,16,(9)
MLA：
Hang Zhou,et al."Establishing a nomogram for stage IA-IIB cervical cancer patients after complete resection".Asian Pacific journal of cancer prevention : APJCP 16..9(2015):3773-7
